Publications by authors named "Natalia M Pelet-Del Toro"

Article Synopsis
  • * A review of various safety data sources found that the incidence of GI-related adverse reactions from topical clindamycin is extremely low, only 0.000045%.
  • * In clinical trials, only 1.4% of participants experienced gastrointestinal AEs, suggesting that concerns about colitis are minimal, although there are limitations in the data's accuracy and generalizability.
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Objective: Hansen's disease (HD) is a chronic granulomatous infection endemic in the tropics. Its main clinical manifestations involve the cutaneous, nervous, and musculoskeletal systems. Leprosy reactions (LR) are systemic inflammatory and immune-mediated complications of HD.

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Article Synopsis
  • This study investigates how often psoriasis patients stop their biologic therapy and looks at the demographics and health characteristics of these patients.
  • A total of 77 psoriasis patients who had discontinued biologic therapy at least once were analyzed, revealing that common comorbidities included hypertension and diabetes, while adalimumab and ustekinumab were the most used biologics.
  • The main reason for stopping therapy was lack of effectiveness, with insurance coverage also affecting the discontinuation of certain biologics; findings showed no significant links between therapy discontinuation and patient demographics.
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Background: Esophageal injuries are rare, life-threatening, events with an overall reported incidence of less than 3%. In rare cases, trauma due to blunt or penetrating injuries cause esophageal perforations, which account for less than 15% of all esophageal injuries.

Materials And Methods: A case-series study was conducted to describe the outcomes and management of all the traumatic esophageal injuries at the Puerto Rico Trauma Hospital (PRTH) from 2000 through 2017.

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