Antibiotics Act with vB_AbaP_AGC01 Phage against in Human Heat-Inactivated Plasma Blood and Models.

Increasing multidrug resistance has led to renewed interest in phage-based therapy. A combination of the bacteriophages and antibiotics presents a promising approach enhancing the phage therapy effectiveness. First, phage candidates for therapy should be deeply characterized.

Environmental Phage-Based Cocktail and Antibiotic Combination Effects on Biofilm in a Human Urine Model.

The emergence of multidrug-resistant (MDR) bacterial infections poses a catastrophic threat to medicine. The development of phage-based therapy combined with antibiotics might be an advantageous weapon in the arms race between human and MDR bacteria. A cocktail composed of the MDR infecting bacteriophages with high lytic activity was used in combination with antibiotics to destroy a bacterial biofilm in human urine.

Characterization of the Three New Kayviruses and Their Lytic Activity Against Multidrug-Resistant .

The development of antimicrobial resistance has become a global concern. One approach to overcome the problem of drug resistance is the application of bacteriophages. This study aimed at characterizing three phages isolated from sewage, which show lytic activity against clinical isolates of multidrug-resistant .