Cationic fluorinated micelles for cell labeling and F-MR imaging.

Magnetic resonance imaging (MRI) relies on appropriate contrast agents, especially for visualizing transplanted cells within host tissue. In recent years, compounds containing fluorine-19 have gained significant attention as MRI probe, particularly in dual H/F-MR imaging. However, various factors affecting probe sensitivity, such as fluorine content and the equivalency of fluorine atoms, must be considered.

Long-term dissolution of thermo- and pH-responsive, F magnetic resonance-traceable and injectable polymer implants.

F magnetic resonance (F MR) tracers stand out for their wide range of applications in experimental and clinical medicine, as they can be precisely located in living tissues with negligible fluorine background. This contribution demonstrates the long-term dissolution of multiresponsive fluorinated implants designed for prolonged release. Implants were detected for 14 (intramuscular injection) and 20 (subcutaneous injection) months by F MR at 4.

Iron-based compounds coordinated with phospho-polymers as biocompatible probes for dual P/H magnetic resonance imaging and spectroscopy.

In this work, we present the synthesis and evaluation of magnetic resonance (MR) properties of novel phosphorus/iron-containing probes for dual P and H MR imaging and spectroscopy (MRI and MRS). The presented probes are composed of biocompatible semitelechelic and multivalent phospho-polymers based on poly(2-methacryloyloxyethyl phosphorylcholine) (pMPC) coordinated with small paramagnetic Fe ions or superparamagnetic maghemite (γ-FeO) nanoparticles via deferoxamine group linked to the end or along the polymer chains. All probes provided very short H T and T relaxation times even at low iron concentrations.