Publications by authors named "Natalia Ingrid Oliveira da Silva"
Article Synopsis
- Ilhéus virus (ILHV) is an arbovirus found in Central and South America and the Caribbean, first identified in 1944, with limited studies on its pathogenesis and vector competence.
- Researchers developed a murine model to study ILHV, demonstrating that it can cause severe neurological disease in mice, particularly in immunocompromised and age-specific groups.
- The virus was shown to replicate efficiently in various vertebrate and invertebrate cell lines, and studies suggest that certain mosquito species can effectively transmit ILHV, indicating a risk of the virus emerging in new regions.
Bovine serum albumin nanoparticles induce histopathological changes and inflammatory cell recruitment in the skin of treated mice.
Biomed Pharmacother
November 2018
Albumin is a natural, biocompatible, biodegradable and nontoxic polymer and due to these features, nanoparticles made of albumin are a good system for drug or antigen delivery. Polymeric nanoparticles are being widely explored as new vaccines platforms due to the capacity of those nanoparticles to prime the immune system by providing sustained release of the antigen after injection. Biodegradable nanoparticles associated with proteins represent a promising method for in vivo delivery of vaccines.
View Article and Find Full Text PDFSerum albumin nanoparticles vaccine provides protection against a lethal Pseudomonas aeruginosa challenge.
Vaccine
October 2018
Pseudomonas aeruginosa is an opportunistic pathogen that causes severe infections in immunocompromised individuals and in patients with cystic fibrosis. A range of vaccines to prevent infections caused by P. aeruginosa has already been tested, yet no vaccine against this pathogen is currently available.
View Article and Find Full Text PDF