Publications by authors named "Natalia H Nagy"
Article Synopsis
- Tumor-associated macrophages (TAMs) are important in prostate cancer and common orthotopic models do not accurately represent the tumor microenvironment.
- Genetically engineered mouse models, specifically Hi-Myc and TRAMP, have been studied to understand TAM characteristics and their role in tumor progression.
- The Hi-Myc model shows a higher density of TAMs and is suggested to better reflect human prostate cancer, making it a more suitable option for developing novel therapies targeting the TME.
