Restless legs syndrome and quality of sleep in patients with glomerulopathy.

Background: Despite a confirmed association between restless legs syndrome (RLS) and end-stage renal disease (ESRD), there is no study on patients presenting with nephrotic syndrome (NS). To investigate the frequency of RLS and poor quality sleep in NS-patients secondary to primary glomerulopathy with nearly normal glomerular filtration rate (GFR) and its associated factors.

Methods: Patients with NS, defined as 24 h-urine protein greater than 3.

Proteinuria is associated with quality of life and depression in adults with primary glomerulopathy and preserved renal function.

Background: There is no information about HRQoL, depression and associated factors in adult with nephrotic syndrome-associated glomerulopathy.

Methodology/principal Findings: Patients with primary glomerulopathy where compared with age and sex-matched hemodialysis patients and healthy subjects. Laboratory data, medical history, comorbid conditions were collected to evaluate factors associated with HRQoL (SF-36) and Depression (Hamilton Depression Rating Scale-HAMD).