Publications by authors named "Natalia Dekhnich"
Article Synopsis
- * A study evaluated a new Sanger sequencing test on 25 pure culture samples, showing 100% sensitivity for clarithromycin and high sensitivity (93%) and specificity (92%) for levofloxacin resistance detection.
- * In clinical tests on 112 patients, resistance mutations were found in 24% for clarithromycin and 23% for levofloxacin, with specific mutations identified, emphasizing the importance of personalized therapy to combat antibiotic resistance.
is one of the most common cause of human infections. Infected patients develop chronic active gastritis in all cases, which can lead to peptic ulcer, atrophic gastritis, gastric cancer and gastric MALT-lymphoma. The prevalence of infection in the population has regional characteristics and can reach 80%.
View Article and Find Full Text PDFAdverse Event Profile During the Treatment of Helicobacter pylori: A Real-World Experience of 22,000 Patients From the European Registry on H. pylori Management (Hp-EuReg).
Am J Gastroenterol
June 2021
Introduction: The safety of Helicobacter pylori eradication treatments and to what extent adverse events (AEs) influence therapeutic compliance in clinical practice are hardly known. Our aim was to assess the frequency, type, intensity, and duration of AEs, and their impact on compliance, for the most frequently used treatments in the "European Registry on Helicobacter pylori management."
Methods: Systematic prospective noninterventional registry of the clinical practice of European gastroenterologists (27 countries, 300 investigators) on the management of H.
Background: Efficacy of Helicobacter pylori eradication therapy depends on the chance of having a resistant H. pylori strain, which is ultimately related to the local antimicrobial resistance epidemiology.
Aim: To assess H.