Titers of ABO antibodies in group O blood donors.

Background: Plasma components of group O blood donations are rarely submitted to ABO antibody titrations even though it is well known that passively acquired antibodies may destroy the recipient's own red cells and tissue grafts.

Objective: Thus, group O donations stratified by gender and age were randomly titrated to identify the best source of products for apheresis and exsanguinous transfusion.

Methods: Samples from 603 blood donors were tested by ABO antibody titration using the conventional tube technique at room temperature.