Corneal thickness, endothelial cell density, and morphological and morphometric features of corneal endothelial cells in goats.

OBJECTIVE To determine corneal thickness (CT), endothelial cell density (ECD), and morphological and morphometric features of caprine eyes and to assess effects of aging on these variables. SAMPLE 27 healthy eyes of 19 Murciano-Granadina goats. PROCEDURES Goats were classified into 2 age groups (kids, 14 months old [14 eyes]; and adults, 7 to 10 years old [13 eyes]).

Endothelial cell density and characterization of corneal endothelial cells in the Tawny Owl (Strix aluco) using specular microscopy.

Objective: To determine endothelial cell density (ECD) and morphology and morphometry of corneal endothelial cells in the tawny owl (Strix aluco), as well as to report the effects of aging on these parameters.

Animal Study And Procedures: Twenty tawny owls were included in the study and classified into 2 groups according to their age: fledglings (<1 year old) and adults (>1 year old). Central corneal endothelium was studied by means of noncontact specular microscopy (Specular Microscope SP-2000P; Topcon, Tokyo, Japan), and results for ECD (cells/mm ), mean cell area ((MCA (μm )), polymegathism (CV), and pleomorphism (% hexagonal cells) were obtained.

A dose-escalation ex vivo study on the effects of intracameral benzalkonium chloride in rabbits.

Background: Rabbits are currently not a good model for studying diseases of the corneal endothelium because their corneal endothelial cells (CECs) maintain a high proliferative capacity throughout almost all their life. Addressing this particular feature might allow the use of this species for such a purpose. The aim of this study was to evaluate the corneal endothelial injury after intracameral benzalkonium chloride (BAC) injection into rabbit eyes ex vivo, and to establish the most suitable starting dose for an in vivo study aimed at developing an animal model of corneal endothelial disease.

Effect of topical 1% cyclopentolate hydrochloride on tear production, pupil size, and intraocular pressure in healthy Beagles.

Objective: The objective of the study was to evaluate the effect of topical 1% cyclopentolate hydrochloride (CH) on tear production (TP), pupil size (PS), and intraocular pressure (IOP) in dogs.

Animal Studied: Fifteen healthy beagle dogs from the UAB research-teaching colony.

Procedure: Dogs without ocular diseases were included.

Effects of age and breed on corneal thickness, density, and morphology of corneal endothelial cells in enucleated sheep eyes.

Objective: The purpose of the study was to determine corneal thickness (CT), endothelial cell density (ECD), morphology, and morphometry in ovine eyes, and to report the effects of age and breed on these parameters.

Animals Studied And Procedures: Forty-eight healthy ovine eyes were classified into six groups (eight eyes per group) according to animals' age (lambs and adults) and breed (Manchega, Ripollesa, and Rasa Aragonesa). Endothelial cell density (cells/mm(2) ) and CT (μm) were calculated in the central cornea and four peripheral quadrants by means of specular microscopy.