Publications by authors named "Natalia Chermont"
Stem Cell Reports
August 2024
Article Synopsis
- Microglia, although typically known for their immune functions in the central nervous system, also play crucial roles in brain development that are not yet fully understood, especially in humans.
- Researchers used human microglia-like cells with a deleted MECP2 gene to study its impact, discovering that this disruption led to significant issues in cell functions like phagocytosis and synapse formation.
- A drug called ADH-503 was found to enhance phagocytosis and restore normal synapse formation, offering potential new treatment options for conditions linked to MECP2 abnormalities in mice.
