Publications by authors named "Natalia C Gutierrez"

Article Synopsis
  • - Undergraduate students at UCLA conducted research using RNA interference (RNAi) and fluorescent proteins to pinpoint genes crucial for blood cell development in fruit flies, screening around 3,500 genes and finding 137 that affected hematopoiesis.
  • - By targeting RNAi to different cell types involved in blood cell maturation, the researchers identified specific gene subsets that either facilitate or inhibit this process, revealing new insights into gene functions related to RNA processing and vesicular trafficking.
  • - The CURE (Course-Based Undergraduate Research Experience) model not only enhanced students' understanding and skills in science but also improved retention rates in STEM fields, demonstrating the value of hands-on research in education.
View Article and Find Full Text PDF

Aim: The aim of this study is to evaluate the effect of silane (Si) application and different adhesive systems on the bond strength of composite resin repair.

Materials And Methods: One hundred composite truncated cone-shaped specimens were prepared and submitted to 5,000 thermal cycles to simulate existing restorations. Their top surfaces were airborne particle abraded with aluminum oxide, etched with phosphoric acid, and divided into two groups ( = 50) with or without Si application.

View Article and Find Full Text PDF

Purpose: To evaluate the influence of different surface treatments on roughness and bond strength of composite repairs.

Materials And Methods: 120 truncated conical specimens were prepared with composite Grandio SO (VOCO) and submitted to 5000 thermal cycles. Specimens were divided into 12 groups (n = 10) regarding the surface treatments: negative control (NC), without treatment; medium-grit diamond bur (MGD); coarse-grit diamond bur (CGD); conventional carbide bur (ConC); crosscut carbide bur (CutC); chemical vapor deposition diamond bur (CVD); sandblasting with aluminum oxide (AlO); Er:YAG laser 200 mJ/10 Hz (Er200); Er:YAG laser 60 mJ/10 Hz (Er50); Nd:YAG laser 120 mJ/15 Hz (Nd120); Nd:YAG laser 60 mJ/ 15Hz (Nd60); air abrasion with 110-μm silica modified aluminum oxide (Rocatec Plus-3M) (SIL).

View Article and Find Full Text PDF

Purpose: This study examined the effects of matrix metalloproteinase-inhibiting solutions and aging methods on the bond strength between resin composite and human dentin.

Materials And Methods: Crown segments of 105 human non-carious molars were bonded using simulated pulpal pressure at 20 cm water pressure. The teeth were randomly split into 5 groups according to the solution applied: CG (control, no solution), CHX (0.

View Article and Find Full Text PDF

The purpose of this study was to investigate the effect of CPP-ACP treatment and Nd:YAG laser on microtensile bond strength (µTBS) of softened dentin. Sixty samples were obtained from thirty sound third molars. All samples were submitted to dentin softening procedure, by the immersion of the specimens in 30 mL of Sprite Zero for 30 min.

View Article and Find Full Text PDF

Objective: The aim of this study was to evaluate the 2-year clinical performance of class II restorations made with a composite resin with two different viscosities.

Methods: 47 patients received two class II restorations (n=94), one made with GrandioSO (conventional viscosity - CV), and the other with GrandioSO Heavy Flow (flowable viscosity - FV), subjecting both materials to the same clinical conditions. The self-etching adhesive Futurabond M was used for all restorations.

View Article and Find Full Text PDF