Publications by authors named "Natalia Bakulina"

Article Synopsis
  • A study examined how different reasons for testing for Helicobacter pylori (H. pylori) affect treatment prescriptions and their success rates across Europe from 2013 to 2023.
  • Out of 53,636 cases, the most common reasons for testing included dyspepsia with normal endoscopy and various types of ulcers, with treatment effectiveness ranging from 87% to 91% based on the indication.
  • Patients with ulcers and preneoplastic lesions experienced higher treatment success and compliance, while those tested for dyspepsia had higher rates of adverse effects.
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Article Synopsis
  • The study aimed to examine the prevalence of Helicobacter pylori (H. pylori) infection in Russia by comparing data from 2017 and 2019, focusing on patients in ambulatory care settings.
  • The analysis included 19,875 subjects, revealing the highest infection rates in the Southern and North Caucasian federal districts, with significant decreases in prevalence observed in several areas between the two years.
  • Overall, H. pylori infection was found to be lower than expected (38.8%), with the highest rates among individuals aged 41-50, while younger and older populations did not show much change over the years.
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Chronic liver disease (CLD), manifested as hepatic injury, is a major cause of global morbidity and mortality. CLD progresses to fibrosis, cirrhosis, and-ultimately-hepatocellular carcinoma (HCC) if left untreated. The different phenotypes of CLD based on their respective clinical features and causative agents include alcoholic liver disease (ALD), non-alcoholic fatty liver disease (NAFLD), metabolic-associated fatty liver disease (MAFLD), and drug-induced liver injury (DILI).

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Background/aim: To estimate the prevalence of autoimmune atrophic gastritis (AAG) in the Russian Federation, a systematic screening of asymptomatic healthy adults by non-invasive biomarker testing was conducted. The aim was i) To test the validity of non-invasive serological screening for AAG; ii) to establish the prevalence of AAG among asymptomatic adults.

Patients And Methods: Altogether, 1,283 asymptomatic, healthy adults (mean age: 38 years) were screened by GastroPanel test.

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Introduction: The objective of the study was to evaluate the prevalence of Clostridium difficile-associated diarrhoea (CDAD) among hospitalised patients with antibiotic-associated diarrhoea (AAD) in general and by specific types of medical care and hospital units.

Methods: A prospective, cross-sectional, non-interventional, multicentre study. The main inclusion criteria were: patient age ≥ 18 years, hospital stay of at least 48 h, current antibiotic therapy or antibiotic therapy within the previous 30 days, loose stools (Bristol stool types 5-7 and stool frequency ≥ 3 within ≤ 24 consecutive hours or exceeding normal for the patient) and signed informed consent form.

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