Publications by authors named "Natalia A Zeninskaya"
Botulism is one of the most serious food intoxications, manifesting as prolonged paralytic conditions. This disease is usually the result of the consumption of poor quality canned or smoked foods, so the inhabitants of many countries of the world are exposed to the risk of this kind of poisoning every year. In view of the severity of poisonings caused by botulinum neurotoxins, monoclonal antibodies (mAbs) show great promise because of their targeting action, lack of allergic reactions and serum sickness.
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- Live anthrax vaccine using attenuated Bacillus anthracis spores is utilized in Russia and CIS countries to prevent anthrax.
- The study examined how long specific antibodies related to spore antigens and protective factors persist in donors after vaccination, and how these levels relate to the ability to neutralize toxins.
- Findings revealed that antibodies can last over a year post-vaccination, with a moderate correlation between antibody levels and neutralization activity in the donors’ blood.