Histological and immunohistochemical changes in facial skin treated with combined ablative and non-ablative laser therapy.

Background: Facial skin rejuvenation is a highly sought after procedure. Different materials, energy-based devices and techniques have been shown to offer good results in facial rejuvenation.

Aims: The aim of this study was to evaluate the macroscopic and histological and immunohistochemical changes in facial skin treated with a combined laser therapy.