Publications by authors named "Nataliіa A Strutynska"
Article Synopsis
- The study examines how aging affects protective mechanisms in the body, particularly focusing on ATP-sensitive potassium channels and their role in heart protection via pyridoxal-5-phosphate (PLP) treatment.
- Experiments were conducted on adult and aged rats to assess the impact of PLP on heart health, including mRNA and protein expressions of potassium channels, heart tissue morphology, and responses in cardiac function during stress tests.
- Results indicated that PLP treatment in older rats reduced heart fibrosis, improved heart function under stress, and increased the expression of specific potassium channel subunits while also reducing oxidative stress markers, suggesting a potential therapeutic benefit of PLP through enhanced potassium channel activity and production of protective substances.