Publications by authors named "Natacha F Pereira"
Genetic Basis of Antimicrobial Resistant Gram-Negative Bacteria Isolated From Bloodstream in Brazil.
Melise Chaves Silveira Cláudio Marcos Rocha-de-Souza Ivson Cassiano de Oliveira Santos Leilane da Silva Pontes Thamirys Rachel Tavares E Oliveira Natacha Ferreira Pereira
Front Med (Lausanne)
March 2021
Article Synopsis
- Multidrug-resistant gram-negative bacilli (GNB) are a significant global health issue, especially when linked to bloodstream infections (BSI), which worsen patient outcomes.
- Whole-genome sequencing was used to study these pathogens in Brazil, revealing high-risk clones like CC258, ST79, and ST233, along with their resistance mechanisms.
- Key findings included associations between specific gene variants and clones, the identification of new MDR clone ST3079, and a novel clonal profile ST848, which could inform future strategies for managing BSI and other hospital-acquired infections.
Article Synopsis
- - Emergence of colistin-resistant bacteria with mobile resistance genes is a growing threat to both animals and humans involved in food production.
- - The article focuses on identifying a specific plasmid that carries colistin resistance genes in poultry, highlighting its role as a new reservoir for these genes.
- - Three closely related bacterial strains were isolated from cloacal swabs, and their genomes included a significant plasmid that potentially facilitates the spread of colistin resistance.