Perfluorosulfonic Acid Membranes with Short and Long Side Chains and Their Use in Sensors for the Determination of Markers of Viral Diseases in Saliva.

The development of accessible express methods to determine markers of viral diseases in saliva is currently an actual problem. Novel cross-sensitive sensors based on Donnan potential with bio-comparable perfluorosulfonic acid membranes for the determination of salivary viral markers (-acetyl--methionine, -carnitine, and -lysine) were proposed. Membranes were formed by casting from dispersions of Nafion or Aquivion in -methyl-2-pyrollidone or in a mixture of isopropyl alcohol and water.

Correlation between Nafion Morphology in Various Dispersion Liquids and Properties of the Cast Membranes.

Nafion is a perfluorosulfonic acid polymer that is most commonly used in proton-exchange membrane fuel cells. The processes of pretreatment and formation of such membranes strongly affect their properties. In this work, dispersions of Nafion in various ionic forms and dispersing liquids (ethylene glycol, -dimethylformamide, -methyl-2-pyrrolidone and isopropyl alcohol-water mixtures in different ratios) were obtained and studied.