[PET in thyroid cancers].

FDG PET can detect thyroid cancer in patients referred for exploration of a different cancer. Because of its lack of specificity, however, this modality is not indicated for examination of thyroid nodules: ultrasonography and fine needle biopsy with cytology allow histological diagnosis, which can be completed by iodine-123 scintigraphy when an autonomous nodule is suspected. No information is currently available about the utility of FDG PET in preoperative staging.

Usefulness of combination of high-resolution ultrasonography and dual-phase dual-isotope iodine 123/technetium Tc 99m sestamibi scintigraphy for the preoperative localization of hyperplastic parathyroid glands in renal hyperparathyroidism.

Background: The usefulness of both dual-phase dual-isotope iodine 123 ( 123 I)/technetium Tc 99m ( 99m Tc) sestamibi scintigraphy and ultrasonography for the detection of hyperplastic parathyroid glands secondary to renal hyperparathyroidism is rarely addressed; most studies focus on primary hyperparathyroidism. However, it may be crucial to identify and accurately localize hyperplastic glands before surgery.

Methods: To study the usefulness of high-resolution ultrasonography (performed by both the radiologist and surgeon) and dual-phase dual-isotope 123 I/ 99m Tc sestamibi scintigraphy in patients with renal hyperparathyroidism, a series of 20 patients consecutively referred for parathyroidectomy was studied prospectively.

Detection of recurrent colorectal carcinoma by 18F-FDG: comparison of the clinical performances of FDG PET and FDG CDET.

Objectives: To assess the clinical performance of fluorodeoxyglucose positron emission tomography (FDG PET) using either a coincidence (CDET) gamma camera or PET equipment with Nal crystals for the detection of recurrences of colorectal cancer.

Methods: From July 1997 to December 1999, 290 examinations were performed in 244 patients using a CDET gamma camera (2-dimensional system with 19 mm thick crystals). Additionally, from January 2000 to July 2002, 354 examinations were performed in 303 patients using PET (3-dimensional system with Nal crystals).

Positron emission tomography with [(18)F]FDOPA and [(18)F]FDG in the imaging of small cell lung carcinoma: preliminary results.

Small cell lung carcinomas (SCLC) express neuroendocrine markers, and dihydroxyphenylalanine (DOPA) is known to accumulate in neuroendocrine tumours. This study was performed with the aim of evaluating the uptake of 3,4-dihydroxy-6-(18)F-fluoro-phenylalanine ([(18)F]FDOPA) by SCLC, based on comparison with the results of fluorine-18 fluorodeoxyglucose ([(18)F]FDG) positron emission tomography (PET) and standard imaging procedures. [(18)F]FDG PET and [(18)F]FDOPA PET were performed on four patients with newly diagnosed SCLC.