A Protocol Investigation Comparing Transcatheter Repair with the Standard Surgical Procedure for Secondary Mitral Regurgitation.

Secondary mitral regurgitation (SMR) is characterized by a pathological process impacting the left ventricle (LV) as opposed to the mitral valve (MV). In the absence of structural alterations to the MV, the expansion of the LV or impairment of the papillary muscles (PMs) may ensue. A number of technical procedures are accessible for the purpose of determining the optimal resolution for MR.

European S2k guidelines for hidradenitis suppurativa/acne inversa part 2: Treatment.

Introduction: This second part of the S2k guidelines is an update of the 2015 S1 European guidelines.

Objective: These guidelines aim to provide an accepted decision aid for the selection, implementation and assessment of appropriate and sufficient therapy for patients with hidradenitis suppurativa/acne inversa (HS).

Methods: The chapters have been selected after a Delphi procedure among the experts/authors.

External Scaffold for Strengthening the Pulmonary Autograft in the Ross Procedure.

Despite offering several potential benefits over standard prosthetic aortic valve replacement, the use of the pulmonary autograft has been limited to date due to concerns over the risk of pulmonary autograft expansion and the need for reintervention. Several techniques using materials with biomimetic potential have been developed to reduce this complication. The incidence, risk factors, and pathophysiology of pulmonary autograft dilatation are discussed in this article.

A tree-based explainable AI model for early detection of Covid-19 using physiological data.

With the outbreak of COVID-19 in 2020, countries worldwide faced significant concerns and challenges. Various studies have emerged utilizing Artificial Intelligence (AI) and Data Science techniques for disease detection. Although COVID-19 cases have declined, there are still cases and deaths around the world.

Analysis of Resin-Based Dental Materials' Composition Depending on Their Clinical Applications.

The objective of this study was to detail the monomer composition of resin-based dental materials sold in the market in 2023 and to evaluate the proportion of bisphenol A (BPA)-derivatives in relation to their applications. A search on manufacturers' websites was performed to reference resin-based dental materials currently on the European market (including the European Union (EU) and United Kingdom (UK). Their monomer composition was determined using material-safety data sheets and was completed by a search on the PubMed database.

Pediatricians' Awareness of Pediatric Psoriasis in the Makkah Region, Saudi Arabia.

Background Psoriasis is an autoimmune disease characterized by the typical appearance of red, thickened, scaly patches on the skin (plaques). These plaques can vary in size and distribution from person to person. In some individuals, it may affect small areas of skin, while in others, large areas covering their body may be involved.

Software defect prediction using learning to rank approach.

Software defect prediction (SDP) plays a significant role in detecting the most likely defective software modules and optimizing the allocation of testing resources. In practice, though, project managers must not only identify defective modules, but also rank them in a specific order to optimize the resource allocation and minimize testing costs, especially for projects with limited budgets. This vital task can be accomplished using Learning to Rank (LTR) algorithm.

Wearable Devices and Explainable Unsupervised Learning for COVID-19 Detection and Monitoring.

Despite the declining COVID-19 cases, global healthcare systems still face significant challenges due to ongoing infections, especially among fully vaccinated individuals, including adolescents and young adults (AYA). To tackle this issue, cost-effective alternatives utilizing technologies like Artificial Intelligence (AI) and wearable devices have emerged for disease screening, diagnosis, and monitoring. However, many AI solutions in this context heavily rely on supervised learning techniques, which pose challenges such as human labeling reliability and time-consuming data annotation.

Isotretinoin-associated acne fulminans: A multicentre, retrospective study of the European Academy of Dermatology and Venereology Task Force on Acne, Rosacea and Hidradenitis Suppurativa.

Background: Acne fulminans (AF) is a rare severe acne entity. Although occasionally reported, it is unclear whether AF development is associated with oral isotretinoin treatment.

Objectives: To investigate the occurrence of isotretinoin-associated AF, clinical characteristics and prognosis at follow-up.

Impacts of the COVID-19 pandemic on subjective wellbeing in the Middle East and North Africa: A gender analysis.

The pathways through which the COVID-19 pandemic has impacted population mental health are potentially gendered. Little research has explored these pathways in low- and middle-income country contexts, such as in the Middle East and North Africa (MENA) region, where socioeconomic roles are highly gendered. To address this gap, we examine the relationships between pandemic-related socioeconomic changes and subjective wellbeing in the MENA region.

Quality of life measurement in rosacea. Position statement of the European Academy of Dermatology and Venereology Task Forces on Quality of Life and Patient Oriented Outcomes and Acne, Rosacea and Hidradenitis Suppurativa.

The European Academy of Dermatology and Venereology (EADV) Task Forces (TFs) on Quality of Life (QoL) and Patient-Oriented Outcomes and Acne, Rosacea and Hidradenitis Suppurativa (ARHS) do not recommend the use of any generic instrument as a single method of Health Related (HR) QoL assessment in rosacea, except when comparing quimp (quality of life impairment) in rosacea patients with that in other non-dermatologic skin diseases and/or healthy controls. The EADV TFs on QoL and Patient-Oriented Outcomes and ARHS recommend the use of the dermatology-specific HRQoL instrument the Dermatology Life Quality Index (DLQI) and the rosacea-specific HRQoL instrument RosaQoL in rosacea patients. The DLQI minimal clinically important difference may be used as a marker of clinical efficacy of the treatment and DLQI score banding of 0 or 1 corresponding to no effect on patients' HRQoL could be an important treatment goal.

A machine learning framework for discovering high entropy alloys phase formation drivers.

In the past years, high entropy alloys (HEAs) witnessed great interest because of their superior properties. Phase prediction using machine learning (ML) methods was one of the main research themes in HEAs in the past three years. Although various ML-based phase prediction works exhibited high accuracy, only a few studied the variables that drive the phase formation in HEAs.

Factors associated with treatment satisfaction in patients with hidradenitis suppurativa: results from the Global VOICE project.

Background: Nearly half of patients with hidradenitis suppurativa (HS) report dissatisfaction with their treatment. However, factors related to treatment satisfaction have not been explored.

Objectives: To measure associations between treatment satisfaction and clinical and treatment-related characteristics among patients with HS.

Ethanol Separation from an Ethanol-Water Solution Using Vacuum Membrane Distillation.

The vacuum membrane distillation (VMD) process was applied to separate ethanol from a simulated ethanol-water solution using a commercial polytetrafluoroethylene (PTFE) membrane. The presence of ethanol in the ethanol-water solution with a 2 wt.% ethanol concentration at a temperature above 40 °C during the MD process may result in membrane failure due to an increase in the chance of the PTFE membrane wetting at high temperatures.

How to Define Mild to Severe Hidradenitis Suppurativa? A Simple New Tool Based on Latent Class Analysis of EPIVER Data Study.

Purpose: Hidradenitis suppurativa (HS) is an inflammatory skin disease characterized by recurrent or chronic painful and suppurating lesions in the apocrine gland-bearing regions. The lack of knowledge about HS and its extremely heterogeneous clinical presentation, in terms of both lesion appearance and sites of involvement, frequently delay its diagnosis for several years. Objectives: in this study, using the latent class analysis, it was demonstrated that severity of HS could be evaluated not only with clinical or surgical characteristics but also with gender specificities.

COVID-19 vaccine uptake and its associated factors among Palestinian healthcare workers: Expectations beaten by reality.

Background: In response to this extraordinary outbreak, many countries and companies rush to develop an effective vaccine, authorize, and deliver it to all people across the world. Despite these extensive efforts, curbing this pandemic relies highly upon vaccination coverage. This study aimed to determine SARS-COV-2 vaccine uptake among Palestinian healthcare workers, the factors that influence vaccination uptake, and the motivators and barriers to vaccination.

Arabic fake news detection based on deep contextualized embedding models.

Social media is becoming a source of news for many people due to its ease and freedom of use. As a result, fake news has been spreading quickly and easily regardless of its credibility, especially in the last decade. Fake news publishers take advantage of critical situations such as the Covid-19 pandemic and the American presidential elections to affect societies negatively.