Publications by authors named "Nassiba Alami Laroussi"

Obesity factors into hypertrophic cardiomyopathy (HCM)-related risk as a disease modifying environmental factor. Behaviours such as diet and sleep are seldom reported upon in children with HCM. It was our aim to report on these factors in this population.

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Article Synopsis
  • Paediatric hypertrophic cardiomyopathy (HCM) is linked to a higher risk of sudden cardiac death, leading to restrictions on physical activity; this inactivity, combined with rising youth obesity, may negatively impact cardiovascular health in these patients.* -
  • The study involved 56 Canadian HCM patients aged 10-19 and evaluated their cardiovascular health using standardized questionnaires; results showed that many had poor health scores similar to those of the general Canadian youth population.* -
  • Findings indicate a significant number of HCM patients have intermediate or poor cardiovascular health, underscoring the need for targeted interventions to encourage healthier lifestyles and improve overall cardiovascular wellbeing.*
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Background: Hypertrophic cardiomyopathy is a burdensome condition that inflicts both physical and psychological impairment on those with the disease, negatively impacting health-related quality of life (HRQoL). Given the abundance of evidence suggesting a role of physical activity (PA) in modulating HRQoL in healthy populations of children, we sought to determine the relationship between HRQoL and PA in children diagnosed with hypertrophic cardiomyopathy.

Methods And Results: A multicenter prospective observational cohort study was conducted, with patients with hypertrophic cardiomyopathy aged 10 to 19 years being provided a wrist-worn activity tracker (Fitbit Charge HR) to wear for 14 days.

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We report the case of a 3-year-old who was highly sensitized and received cardiac transplantation from a donor in the acute phase of SARS-CoV-2 infection. Despite maximal immunosuppression owing to a positive cross-match and desensitization protocol, the patient's course was favorable.

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Introduction: Epstein-Barr virus (EBV) associated smooth muscle tumors (EBV-SMT) are a rare complication of solid organ transplantation (SOT). Incidence data related to this EBV-SMT are limited. EBV DNA is universally present in these tumors.

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Despite reports of successful pregnancies in heart transplant (HTx) recipients, many centers recommend their patients against maternity. We reviewed our provincial experience of pregnancy in HTx recipients by performing charts review of all known gestations following HTx in the province of Quebec (Canada), stratified between planned and unplanned pregnancies. Long-term survival was compared to HTx recipient women of childbearing age who did not become pregnant.

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Introduction: Dilatation of the ascending aorta is described in Turner's syndrome with variable prevalence (6.8-32%). Reported series typically include patients with associated cardiac anomalies.

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