Awareness of isotretinoin use and Saudi FDA pregnancy prevention program in Riyadh, Saudi Arabia: A cross-sectional study among female patients.

Introduction: Oral isotretinoin is an effective agent for the treatment of severe cystic acne. Isotretinoin is a teratogen; there is an increased risk of congenital defects in infants exposed to the drug in the uterus. The Saudi Food and Drug Authority (SFDA) has implemented a pregnancy prevention program (PPP) to protect females from those teratogenic effects.

Interferon-induced transmembrane protein-3 genetic variant rs12252 is associated with COVID-19 mortality.

Interferon-induced membrane proteins (IFITM) 3 gene variants are known risk factor for severe viral diseases. We examined whether IFITM3 variant may underlie the heterogeneous clinical outcomes of SARS-CoV-2 infection-induced COVID-19 in large Arab population. We genotyped 880 Saudi patients; 93.

Rotational relapse of anterior teeth following orthodontic treatment and circumferential supracrestal fiberotomy.

Background/purpose: Several factors cause relapse of orthodontically de-rotated teeth after appliance removal. Circumferential supracrestal fiberotomy (CSF) may release the tension on the supra-alveolar fibers following tooth de-rotation, thereby reducing the relapse risk. However, careful identification of the amount and location of relapse enables proper clinical evaluation.

Saudi Vigilance Program: Challenges and lessons learned.

Pharmacovigilance is vital to public health. Adopting a robust spontaneous reporting system for adverse drug events can counteract most hazards that arise from utilizing medicinal products. Prior to the establishment of the Saudi Food and Drug Authority (SFDA), the number of pharmacovigilance-related activities in Saudi Arabia was limited.

Cephalometric evaluation for Saudi population using the Downs and Steiner analysis.

The purpose of this study is to formulate cephalometric norms of the Saudi population; and to evaluate whether significant cephalometric differences exist between Saudi and Caucasian patients. Lateral cephalometric radiographs of 60 selected Saudis (30 males and 30 females) with esthetically pleasing and harmonious faces, Angle I molar relationship, with all permanent teeth present and no history of orthodontic treatment or facial trauma, age range between 20 and 30 years were analyzed using the Downs and Steiner analysis. The means, standard deviations, and ranges of the measurements were compared with the norms established by Downs and Steiner.

Facial esthetics in a selected Saudi population.

Objective: The purpose of this study is to analyze the soft tissue cephalometric norms of the Saudi population and to evaluate whether significant cephalometric soft tissue differences exist between Saudi and Caucasian population.

Methods: Lateral cephalometric radiographs of 40 selected Saudis with esthetically pleasing faces (20 males and 20 females). The study was carried out in the College of Dentistry, King Saud University, Riyadh, Kingdom of Saudi Arabia between 1999 - 2001.

Time of eruption of primary dentition in Saudi children.

The purpose of the present study was to determine the mean and standard deviation of eruption for primary dentition in children from Saudi Arabia and to compare it with another sample of full-term children who are clinically healthy between the ages of 4-40 months. The results were significantly different from available literature on eruption patterns in children. Moreover, there is a slightly delayed eruption of primary teeth in Saudi children when compared to Caucasians.