Purpose: To evaluate the clinical outcomes of intrastromal corneal ring segment (ICRS) implantation to correct ectasia in eyes with prior refractive surgery.
Methods: Forty-one eyes of 25 patients (13 men, 12 women; mean age, 28.66 years) with ectasia after refractive surgery [photorefractive keratectomy (PRK) or laser in situ keratomileusis (LASIK)] were included in a nonrandomized, retrospective, observational case series.
Purpose: To evaluate changes in corneal sensitivity following corneal cross-linking (CXL) in patients with progressive earlier stage keratoconus.
Methods: Thirty-eight eyes of 19 patients (11 women, 8 men) were included in a prospective, nonrandomized clinical study. The mean patient age was 22 years (range, 18-26 years).
Purpose: To evaluate the thinnest corneal thickness changes during and after corneal collagen cross-linking treatment with ultraviolet-A irradiation, using hypo-osmolar riboflavin solution in thin corneas.
Methods: Eighteen eyes of 18 patients were included in this study. After epithelium removal, iso-osmolar 0.
Purpose: To determine the ten-year visual results and outcomes of excimer laser phototherapeutic keratectomy (PTK) for recurrent corneal erosions.
Methods: Twenty-six eyes of 23 patients with recurrent corneal erosions were treated by PTK from 1996 to 2000 at the Goiania Eye Institute, Brazil. All eyes had failed to respond to conventional therapy.
Purpose: To evaluate the efficacy and safety of mitomycin C (MMC) 0.02% in inhibiting haze formation after excimer laser photorefractive keratectomy (PRK) for residual myopia following radial keratotomy (RK).
Methods: A prospective, nonrandomized, noncomparative interventional case series was conducted of 22 eyes (14 patients) with residual myopia after RK performed at a single institution.
Purpose: To evaluate and compare the effect of hinge position and flap thickness on recovery rate of corneal sensation after (LASIK).
Design: Prospective, randomized clinical study.
Methods: Forty eyes of 40 patients underwent LASIK to correct myopia ranging from -1.
Objective: To evaluate the changes in corneal sensitivity after LASIK for the correction of different degrees of myopia.
Design: Prospective, nonrandomized, comparative self-controlled trial.
Participants: One hundred two myopic eyes of 58 patients were included in this study.
Purpose: To determine the safety, efficacy, predictability, and stability of laser in situ keratomileusis (LASIK) to correct high myopia or high myopic astigmatism in patients with high anisometropia in whom conventional treatments have failed.
Methods: Nine eyes of nine patients, three boys and six girls with high anisometropia (>3.50 D), were included in this study.
Purpose: To determine the safety, efficacy, predictability, and stability of laser in situ keratomileusis (LASIK) to correct myopia and myopic astigmatism in eyes with prior penetrating keratoplasty.
Methods: Eight eyes of 8 patients with penetrating keratoplasty had significant postoperative refractive error. Each eye received LASIK 1 year or more after penetrating keratoplasty.
Background: The capability of the 193-nm excimer laser to ablate the cornea and to remove opacities and various other corneal diseases in a procedure called phototherapeutic keratectomy (PTK) has been demonstrated. In this study we evaluated the long-term results of PTK for treatment of granular and lattice corneal dystrophies.
Methods: Four eyes with granular or lattice corneal dystrophy were treated with a mean follow-up of 47.
J Refract Surg
December 1996
Background: To develop an in vitro model to study the effects of excimer laser keratectomy on corneal stromal cells, we evaluated two types of collagen gel populated with keratocytes.
Methods: Keratocyte-populated collagen gels were prepared with type I collagen in 6-well plates or in culture plate inserts, the bottom of which consisted of a nitrocellulose membrane, contained within 6-well plates. The gels were ablated by the 193-nm excimer laser, set to ablate 50, 100, or 200 microns deep, and was observed under a phase-contrast microscope for 2 days.
Purpose: To determine if keratocyte loss, after removal of the corneal epithelium, can be prevented by a collagen shield used alone or in combination with a topically applied corneal preservation medium.
Methods: Twenty-four New Zealand white rabbits were divided into six groups of four rabbits each. The central 6 mm of corneal epithelium was removed from one eye of each animal by means of a blunt spatula.
Purpose: To evaluate the ability of topical diclofenac to decrease corneal opacity after excimer laser photorefractive keratectomy (PRK).
Methods: Twenty New Zealand white rabbits underwent a unilateral 193-nm excimer laser myopic photorefractive keratectomy to correct 5 diopters. There were four groups of five rabbits each.
Purpose: Mini-radial keratotomy (mini-RK) involves limiting the extent of radial incisions to within 3.5 mm from the center of the central clear zone, compared with incisions that extend close to or beyond the limbus, as with "conventional" RK. This study was designed to determine if shorter incision length reduces the likelihood of corneal rupture after blunt trauma.
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