Stress refers to an organism's response to environmental threats in normal condition to maintain homeostasis in the body. In addition, strong inflammatory reactions induced by the hypothalamic-pituitary-adrenal (HPA) axis under stress condition during a long time. Reciprocally, chronic stress can induce the irritable bowel syndrome (IBS) which is a well-known gut disorder thereby play an important role in the promotion and pathophysiology of neuropsychiatric diseases.
View Article and Find Full Text PDFThe physiological structure and functioning of the brain are determined by activity-dependent processes and affected by "synapse plasticity." Because chemical transmitters target and regulate synapses, exogenous chemical stimulants and transmitters can alter their physiological functions by interacting with synaptic surface receptors or chemical modulators. Caffeine, a commonly used pharmacologic substance, can target and alter synapses.
View Article and Find Full Text PDFThis chapter explores the complex relationship between coffee drinking and stress management, highlighting the advantages and disadvantages of this widely consumed beverage. The chapter explores the physiological, psychological, and social effects of coffee on stress response and resilience through a thorough analysis of recent studies. It highlights the negative consequences of excessive intake on cardiovascular, gastrointestinal, and mental health while also discussing how moderate coffee consumption may lower stress levels, improve coping skills, and promote relaxation.
View Article and Find Full Text PDFFor decades, coffee has held the distinction of being the most commercially prominent food product and the most universally consumed beverage worldwide. Since the inauguration of the inaugural coffee house in Mecca toward the conclusion of the 15th century, coffee consumption has experienced exponential growth across the globe. Coffee, renowned globally as a beloved beverage, contains a diverse array of compounds known to benefit health.
View Article and Find Full Text PDFRationale: Using routine synthetic drugs in the treatment of psychiatric disorders may have some restrictions due to serious side effects and pharmacoresistance. Some natural agents may be promising alternatives in this case. The neuroprotective activity of the neuromodulator adenosine and its receptor, A receptor (AR) in the central nervous system has been mentioned in different studies.
View Article and Find Full Text PDFStroke is a serious cerebrovascular disease that causes post-stress depression and death. Stress and inflammation have pivotal roles in the induction of the disease. Several drugs and agents have been used for the treatment of disease, but their uses are faced with limitations owing to their side effects.
View Article and Find Full Text PDFControversial studies indicate the adenosine compound (a neuromodulator with neuroprotective activity) intervention on cognitive performance. On the other hand, Japanese sake yeast has been enriched with oral adenosine analogs as a novel natural agent. As the first report, we aimed to evaluate the effects of Japanese sake yeast supplement in a mouse model of chronic restraint stress-induced cognitive dysfunction.
View Article and Find Full Text PDFDiabetes is accompanied by inflammation and oxidation. Supplementation of anti-inflammatory and antioxidant compounds can prevent the progression of diabetes. This study aimed to investigate the effects of supplementation of microalgae (NOM) on the inflammatory and antioxidant responses in diabetic rats.
View Article and Find Full Text PDFObjectives: The development of teeth is affected by genetic and environmental factors. Amoxicillin is a widely prescribed semi-synthetic antibiotic. Its most frequent side effects are gastrointestinal disorders and hypersensitivity reactions.
View Article and Find Full Text PDFDiabetes Metab Syndr Obes
July 2018
Objectives: Lipid peroxidation and hyperglycemia are common signs for diabetes. Natural antioxidants such as microalgae (SPM) may prevent lipid peroxidation and hyperglycemia. This study aimed to evaluate the effects of SPM on antioxidant and anti-inflammatory in diabetic rats.
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