How to exercise to increase lipolysis and insulin sensitivity: Fasting or following a single high-protein breakfast.

Background: The purpose of this study was to investigate the lipolysis response and insulin sensitivity to high-intensity interval exercise (HIIE) upon fasting (HIIEFAST) and following the intake of a high-protein breakfast (HIIEHPFED).

Methods: Overweight men participated in two sessions of HIIE after an overnight fast and post-HPFED with an interval of one week. Metabolic biomarkers were assessed before, immediately after, and 3h postexercise.