single nucleotide polymorphisms rs2781666 and rs2781665 confer risk of Type 2 diabetes mellitus.

Genetic polymorphisms mapped in the locus (chr6:131894344-131905472) and their functional effects on type 2 diabetes mellitus (T2DM) have not been thoroughly elucidated to date. The present study aimed to investigate an association between variant alleles at locus and T2DM in patients. Two single nucleotide polymorphisms (SNPs) were characterized in a representative sample of 500 patients with T2DM and 500 healthy volunteers.