Publications by authors named "Nasra Tehyoh"
Article Synopsis
- Ineffective erythropoiesis (IE) leads to anemia in beta-thalassemia, characterized by increased erythroblast proliferation without proper differentiation, resulting in immature red blood cells (RBCs).
- The study investigates the role of microRNA-155 (miR-155) in beta-thalassemia, focusing on its expression in erythroid cells from thalassemic bone marrow and its effects on cell differentiation and proliferation.
- Results show that miR-155 is upregulated during erythropoiesis in thalassemic mice, and manipulating its expression alters erythroid cell proliferation and differentiation, suggesting its potential significance in managing thalassemia-related anemia.
