[Dynamics of the respiratory center activity during electrical stimulation of the diaphragmatic nerve].

The adoption of artificial rhythm of electrical stimulation of diaphragmatic nerve was found to be determined by the force and rate of artificial contractions of the diaphragm, by the concentration of barbiturates in the blood and by gaseous composition of inspired air in anesthetized dogs. The time interval between the onset of artificial contraction and onset of natural one seems to characterize functional activity of respiratory center and to result from inhibitory afferent effect of the lungs' mechanoreceptors, on the one hand, and from activating effects of central and peripheral chemoreceptors, on the other hand.

[Changes in electric stability and ultrastructure of the myocardium in heart rate-decreasing paired stimulation].

Experimental rabbits were subjected to a ventricular rate-decreasing paired pacing over an hour. Ventricular rates showed a 1.4-1.

[Changes in the ischemic myocardium in experimental paired stimulation of the heart].

In dog experiments the dynamics of electrophysiological and morphological indices of the ischemic myocardium in sinus tachycardia was compared with that in deceleration of cardiac contraction under the effect of paired stimulation. Intensification of the damaging effect of a 40-minute occlusion of the coronary artery complicated by destructive changes of the cardiomyocytes was revealed after deceleration of the rhythm; in reperfusion of the ischemic area the effect of electrogram restoration was diminished, which was attended with deeper focal damage to the heart muscle.