Impact of Renal Replacement Therapy on Outcomes of Living Donor Liver Transplantation for Acute Liver Failure: A Cohort Study.

Despite the promising role of renal replacement therapy (RRT) in acute liver failure (ALF), high-risk patients need liver transplantation and remain at risk for death due to cerebral complications. The objective of this study was to report outcomes of living donor liver transplantation (LDLT) for ALF with perioperative RRT. This was a single-center retrospective cohort study.

Genome-wide identification, and gene expression analysis of NBS-LRR domain containing R genes in for unveiling the dynamic contribution in plant immunity against cf. .

Unlabelled: The plant R genes encode the NLR proteins comprising nucleotide-binding sites (NBS) and variable-length C-terminal leucine-rich repeat domains. The proteins act as intracellular immune receptors and recognize effector proteins of phytopathogens, which convene virulence. Among stresses, diseases contribute majorly to yield loss in crop plants, and R genes confer disease resistance against phytopathogens.

Long-term medical and quality of life outcomes among voluntary liver donors.

Background: Long-term medical and quality of life (QOL) outcomes in voluntary liver donors remain under investigated. The objective of the current study was to report long-term medical outcomes and re-evaluate QOL in living liver donors.

Methods: This was a single-center retrospective cohort study of donors who underwent donor hepatectomy between 2012 and 2018.

Empirical phenotyping and genome-wide association study reveal the association of panicle architecture with yield in .

manifests adaptability to grow under varying agro-climatic scenarios. Assessing quinoa germplasm's phenotypic and genetic variability is a prerequisite for introducing it as a potential candidate in cropping systems. Adaptability is the basic outcome of ecological genomics of crop plants.

Rural households' livelihood adaptation strategies in the face of changing climate: A case study from Pakistan.

Rural and agricultural communities' adaptation to climate change has gained significant attention owing to many countries' vulnerability to climate change risks. A similar trend has been witnessed in South Asia, a highly climate-vulnerable region, where research has grown dramatically considering the agriculture sector's vulnerability to climate-induced disasters. However, little attention has been paid to the adaptation of the livelihoods of rural households.

Enhancing specimen collection skills for dried blood spots through an immersive virtual learning environment: a cross-sectional study.

Objective: The quality of dried blood spot (DBS) specimens impacts newborn screening (NBS) results, hence proper training is crucial for DBS specimen collection. To address this, a training module for Allied Health Professionals (AHPs) and nurses was created on Moodle, a virtual learning environment (VLE). The purpose of this research was to determine the feasibility and effectiveness of this module.

Reconnoitering NGOs strategies to strengthen disaster risk communication (DRC) in Pakistan: A conventional content analysis approach.

Risk communication is crucial since individuals need to understand how they are at risk and what proper steps to deal with flood events. Sharing information with the public opens the door for two-way communication about risks, wherein you learn about people's perspectives and work together to find ways to mitigate the risks. Beyond government scope, relief organizations play a big part in advising individuals about the likelihood of catastrophic events as they possess the commonalities that define community engagement.

Dual Graft Living Donor Liver Transplantation for High Acuity Patients: A Single-Center Experience.

Background: The outcomes of dual graft living donor liver transplantation (DGLDLT) in high acuity patients remain underreported. The objective of this study was to report long-term outcomes from a single center in this select group of patients.

Methods: This was a retrospective review of patients who underwent DGLDLT between 2012 and 2017 (n = 10).

Variations in Total Protein and Amino Acids in the Sequenced Sorghum Mutant Library.

Sorghum () is the fifth most important cereal crop worldwide; however, its utilization in food products can be limited due to reduced nutritional quality related to amino acid composition and protein digestibility in cooked products. Low essential amino acid levels and digestibility are influenced by the composition of the sorghum seed storage proteins, kafirins. In this study, we report a core collection of 206 sorghum mutant lines with altered seed storage proteins.

Silicon-Induced Morphological, Biochemical and Molecular Regulation in L. under Low-Temperature Stress.

Climate changes abruptly affect optimum growth temperatures, leading to a negative influence on plant physiology and productivity. The present study aimed to investigate the extent of low-temperature stress effects on date palm growth and physiological indicators under the exogenous application of silicon (Si). Date palm seedlings were treated with Si (1.

Diversity, Lifestyle, Genomics, and Their Functional Role of , , and Species in Environmental Remediation and Plant Growth Promotion under Biotic and Abiotic Stressors.

, , and genera contain various devastating plant pathogens that cause severe crop losses worldwide. The species belonging to these genera also perform a variety of diverse functions, including the remediation of environmental contaminations, beneficial phytohormone production, and maintaining their lifestyle as epiphytes, endophytes, and saprophytes. Recent research has revealed that despite their pathogenic nature, these fungi also play an intriguing role in agriculture.

Survival after extended resections for gallbladder cancer.

Backgrounds/aims: Locally advanced gallbladder cancer (GBC) is associated with survival limited to a few months. Extended resections (ER) are occasionally performed in this group and outcomes remain inconclusive. This study assessed outcomes after ER for locally advanced GBC.

Contriving multi-epitope vaccine ensemble for monkeypox disease using an immunoinformatics approach.

The current global outbreak of monkeypox (MPX) disease, caused by Monkeypox virus (MPXV), has resulted in 16 thousand infection cases, five deaths, and has been declared a global health emergency of international concern by the World Health Organization. Given current challenges in the safety of existing vaccines, a vaccine to prevent MPX infection and/or onset of symptoms would significantly advance disease management. In this context, a multi-epitope-based vaccine could be a well-suited approach.

Aroma Profile and Biological Effects of Essential Oils: A Comparative Study of Stem, Flowers, and Leaves.

The present analysis explores the chemical constituents and determines the in vitro antimicrobial, antidiabetic, and antioxidant significance of the essential oils (EOs) of the stem, leaves, and flowers of Ochradenus arabicus for the first time. The EOs of the flowers presented seventy-four constituents contributing to 81.46% of the total EOs, with the major compounds being 24-norursa-3,12-diene (13.

Textbook outcome among voluntary donors undergoing major living donor hepatectomy.

Purpose: Textbook outcome (TO) is a composite measure of outcome and provides superior assessment of quality of care after surgery. TO after major living donor hepatectomy (MLDH) has not been assessed. The objective of this study was to determine the rate of TO and its associated factors, after MLDH.

Effects of micro-nano bubble with CO treated water on the growth of Amaranth green (Amaranthus viridis).

The micro and nano bubble (MNB) technology, due to its promising features and advantages, has become increasingly popular in agriculture. MNB-treated water positively impacts plant growth, especially when it is treated with a combination of gas-like carbon dioxide (CO), injected through the MNB generator. Therefore, this study used MNB water with CO that are small bubbles of nanometer and micrometer diameters having several unique physical properties that make them useful for water treatments.

Synergy between climate risk perception, adaptation responses, and agricultural productivity: the case of rice farming communities in Pakistan.

The climate variability in Pakistan adversely affects rice crops and undermines the food security and livelihoods of millions of rural households whose survival depends directly on rice farming. This study examines farmers' risk perception, adaptation responses, and adaptation impact on rice productivity. We employed a multi-stage sampling method for selecting 480 farmers from the rice production zone of Punjab province, a region that produces more than 60% of the total rice in the country and faces significant production decline due to climate change.

The impact of insecticides and plant extracts on the suppression of insect vector (Bemisia tabaci) of Mungbean yellow mosaic virus (MYMV).

Mungbean yellow mosaic virus (MYMV) is an important constraint in successful production of mungbean (Vigna radiata L.) in many countries, including Pakistan. The MYMV spreads by insect vector whitefly (Bemisia tabaci Gennadius).

Living Donor Liver Transplantation During the COVID-19 Pandemic: an Evolving Challenge.

Background: Maintaining standards of living donor liver transplantation (LDLT) can be a challenge during the corona virus disease 2019 (COVID-19) pandemic. Center-specific protocols have been developed and transplant societies propose limiting elective LDLT. We have looked at outcomes of LDLT during the pandemic in an exclusively LDLT center.

Livelihood diversification in managing catastrophic risks: evidence from flood-disaster regions of Khyber Pakhtunkhwa Province of Pakistan.

Pakistan's agricultural productivity is considered to be low despite several agriculture promotion policies. Such policies concentrate primarily on on-farm development and overlook rich prospects for off-farm diversification. Livelihood diversification of small-scale farmers plays a major role in reducing hunger and mitigating the adverse impacts of climate change.

Living Donor Liver Transplantation for Hepatocellular Carcinoma: Appraisal of the United Network for Organ Sharing Modified TNM Staging.

In deceased donor liver transplantation (DDLT), transplant eligibility for T3-T4 HCC requires successful downstaging (DS). Living donor liver transplantation (LDLT) can be considered selectively in these patients without DS, but its role is not defined. The objective of the current study was to assess outcomes of LDLT for HCC based on UNOS staging with no prior DS.

Mapping farmers' vulnerability to climate change and its induced hazards: evidence from the rice-growing zones of Punjab, Pakistan.

In developing countries like Pakistan, agriculture constitutes the primary source of support for the majority of rural and the adjacent urban population. Despite the large part it plays in the economy, it faces significant challenges caused by climate change, such as rising temperatures, floods, droughts, and yield losses. In Pakistan, rice, which is the second most essential food crop and livelihood source for the millions of farm households, is facing significant yield reduction due to climate change.

Public institutions' capacities regarding climate change adaptation and risk management support in agriculture: the case of Punjab Province, Pakistan.

Public institutions could play an important role in building agricultural resilience to climate change by providing information and technology support to farmers. This study takes the case of Pakistan to investigate the perspective and capacities of public institutions as well as to identify gaps in current institutional arrangements in dealing and managing climate change in the agriculture sector. For this purpose, 53 office bearers from thirteen public institutions in Punjab province of Pakistan were interviewed using a semi-structured questionnaire to collect data on climate knowledge, training, coordination, and resource availability.

Best achievable results need territorial familiarity: Impact of living donor liver transplant experience on outcomes after pancreaticodoudenectomy.

Background: Recently, benchmarks for pancreatic surgery have been proposed. Living donor liver transplantation (LDLT) is thought to have a positive impact on PD outcomes. The objective of the current study was to determine if the proposed benchmark cutoffs are achievable in an LDLT program with low to medium volumes for PD.