Association of variant of vitamin D receptor gene with polycystic ovary syndrome: A case-control study.

Background: Polycystic ovarian syndrome (PCOS) is an endocrine disorder that affects women's fertility and causes alterations such as obesity, insulin resistance, menstrual irregularities, and polycystic ovaries. The results of the studies show that the issue of vitamin D and vitamin D receptor (VDR) is controversial for PCOS susceptibility.

Objective: To investigate the association of polymorphism in the gene with metabolic parameters in obese PCOS women.