Synthetic approaches for novel fused pyrimidine derivatives: Design, structural characterization, antiviral, antitumor, and molecular docking evaluation.

The goal of this work was to synthesize new compounds for anticancer evaluation as a trial to obtain new antitumor agents with higher activity and fewer side effects. Therefore, the precursor 2,2'-(1,4-phenylenebis (thiazole-4,2-diyl))bis (3-(dimethylamino)acrylonitrile) was used to synthesize various azolopyrimidine derivatives connected to the thiazole moiety. Compounds -, including pyrazolopyrimidine, triazolopyrimidine, and others, were produced by reacting enaminonitrile with different -nucleophiles.

Optical, Opto-Mechanical, and Antimicrobial Characterization of TiO and ZnO-Enhanced Polypropylene Fibers Using Interferometric Techniques and Fourier Transform Analysis.

This study investigates the optical, mechanical, and antimicrobial properties of polypropylene (PP) fibers enhanced with titanium dioxide (TiO) and zinc oxide (ZnO) nanoparticles. Using a Mach-Zehnder interferometric system, we examined the refractive indices, birefringence, and opto-mechanical behavior of blank PP, PP/TiO, and PP/ZnO nanocomposite fibers under various conditions, including different polarization orientations and during cold drawing processes. The 2D Fourier transform algorithm is employed to analyze interferometric data, enabling precise measurements of refractive index profiles and birefringence.

Novel amino-functionalized MOF-based sensor for zinc ion detection in water and blood serum samples.

Aquatic systems with low zinc levels can experience a significant decrease in carbon dioxide uptake and limited growth of phytoplankton species. In this study, we describe the use of a new fluorescent sensor based on NH-MIL-53(Al), and modified with glutaraldehyde and sulfadoxine, for selectively detecting zinc ions in water and blood serum samples. Characterization of the synthesized material was performed using X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), Brunauer-Emmett-Teller (BET) surface area analysis, X-ray photoelectron spectroscopy (XPS), and scanning electron microscopy (SEM), confirming successful functionalization and preservation of the MOF structure.

Molecular modelling and antimicrobial activity of newly synthesized benzothiazolo[3,2-]pyrimidine clubbed thiazole derivatives.

A series of benzothiazolopyrimidine-thiazole conjugates , , and were produced through the reactions of 8-acetylbenzothiazolopyrimidine-thiosemicarbazone compound with chloroacetone, (un)substituted phenacyl chlorides, and ethyl chloroacetate, respectively. Based on DFT study, the synthesized conjugates had a twisted shape, except for the parent benzothiazolopyrimidine and its thiosemicarbazone compound , which were flat. The study of FMO's also showed that the substituted thiazole derivatives and have equivalent configurations of HOMO and LUMO, as well as exhibiting the least FMO's gap (ΔE).

Synthesis of designed new 1,3,4-oxadiazole functionalized pyrano [2,3-f] chromene derivatives and their antimicrobial activities.

Diethyl 2-(((4-methyl-2-oxo-2H-chromen-7-yl)oxy)methylene)malonate was synthesized from coumarin 1 and diethyl ethoxymethylene malonate in ethanol, followed by cyclization in diphenyl ether to give chromene-9-carboxylate . Sugar hydrazones were formed by reacting hydrazide with D-galactose, D-mannose, and D-xylose, then acetylated to per--acetyl derivatives . Heating with acetic anhydride at 100 °C gave oxadiazolines .

An effective procedure used metal-organic framework for determination of cadmium ions in real tap water and human blood plasma samples.

A newly developed 2H5MA-MOF sensor by covalently linking NH-MIL-53(Al) with 2'-Hydroxy-5'-methylacetophenon, designed for highly sensitive and selective detection of Cd ions using fluorometric methods. Detailed structural and morphological analyses confirmed the sensor's unique properties. It demonstrated an impressive linear detection range from 0 to 2 ppm, with an exceptionally low detection limit of 5.

Enhancing methyl violet 2B pollutant removal from wastewater using Al-MOF encapsulated with poly (itaconic acid) grafted crosslinked chitosan composite sponge: Synthesis, characterization, DFT calculation, adsorption optimization via Box-Behnken Design.

In this research, aluminum metal-organic framework encapsulated with poly (itaconic acid) grafted crosslinked chitosan composite sponge (Al-MOF@PIC) was prepared. SEM, FTIR, XPS, XRD, and BET techniques were employed to thoroughly characterize the synthesized material and establish its structure and characteristics. The study discovered that the Al-MOF@PIC is an efficient way to remove dyes, which constitute a significant number of contaminants in industrial wastewater.

Synthesis, characterization and adsorption optimization of bimetallic La-Zn metal organic framework for removal of 2,4-dichlorophenylacetic acid.

To eliminate the hazardous pesticide 2,4-dichlorophenylacetic acid (2,4-D) through aqueous solutions, stacked nanorods known as hetero bimetallic organic frameworks (MOFs) of 2-methyl imidazole based on lanthanum and zinc are created. The research's convincing discoveries displayed that La/Zn-MOF is an actual adsorbent for the removal of 2,4-D through aqueous solutions. The La/Zn-MOF was investigated using a variability of techniques, with scanning electron microscope (SEM), powered X-ray diffraction (PXRD), and Brunauer-Emmett-Teller (BET) investigation.

Design, synthesis, and molecular docking of new phenothiazine incorporated -Mannich bases as promising antimicrobial agents.

The present work aims to synthesize four series of phenothiazine incorporation Mannich bases. Therefore, 10-methyl-10H-phenothiazine-3-sulfonamide which was subjected to react with some secondary amines and formaldehyde to give the Mannich bases , and -. Compound was then subjected to react with some secondary amines and formaldehyde to give the corresponding Mannich bases .

Novel Deliberately Sensitive and Selective Tetrahydrozoline Voltammetric Sensors Integrated with a Copper Oxide Nanoparticle/Zeolite Platform.

The present study introduced a novel disposable screen-printed carbon electrodes (SPCEs) modified with copper oxide/zeolite nanostructures for eco-friendly selective differential pulse voltammetric quantification of tetrahydrozoline (THZ) in eyedrop samples and biological fluids. Modification of the electrode matrix with copper oxide nanoparticles/zeolite nanostructures (CuONPs/ZY) with their effective and synergistic electrocatalytic activity enhanced the electrode performance against electrooxidation of THZ at 0.960 V in BR at pH 9.

Correction: Magnetic sodium alginate grafted with waste carbonaceous material for diclofenac sodium removal: optimization of operational parameters and process mechanism.

[This corrects the article DOI: 10.1039/D3RA00495C.].

Tailoring magnetic Sn-MOFs for efficient amoxicillin antibiotic removal through process optimization.

This study investigated the efficacy of magnetic Sn metal-organic frameworks (MSn-MOFs) in removing the insecticide amoxicillin (AMX) from aqueous solutions. Our thorough experimental investigation showed that MSn-MOFs were an incredibly effective adsorbent for removing AMX. Several methods were used to characterize the material.

Inkjet-Printed Sensors Based on Nanoferrite-Doped Manganese Oxide Nanoparticles for the Sensitive Differential Pulse Voltammetric Determination of Brimonidine.

The present study described the construction and the electrochemical futures of a novel inject-printed electrochemical sensor based on spinel ferrite-doped manganese oxide nanoparticles (FMnONPs) for the sensitive differential pulse voltammetric quantification of brimonidine (BRIM) in ophthalmic solutions. At the optimized electroanalytical parameters, calibration graphs were linear within the BRIM concentration range of 24-3512 ng mL and recorded a detection limit value of 8.21 ng mL.

Synthesis of tetrazole hybridized with thiazole, thiophene or thiadiazole derivatives, molecular modelling and antimicrobial activity.

Background: Tetrazole-based derivatives and their electronic structures have displayed interesting antimicrobial activity.

Methods: The tetrazole-based hybrids linked with thiazole, thiophene and thiadiazole ring systems have been synthesized through various chemical reactions. The computational method DFT/B3LYP has been utilized to calculate their electronic properties.

Preparation of Self-Healing Anthocyanidin-Containing Thermochromic Alginate Ink for Authentication Purposes.

Thermochromic inks have proven to be a promising security encoding approach for making commercially available products less susceptible to forgery. However, thermochromic inks have been plagued with poor durability. Thus, self-healable hydrogels can be used as self-repair inks with better durability.

Facile synthesis of new metal-organic framework/chitosan composite sponge for Hg(II) removal: Characterization, adsorption efficiency, and optimization using Box-Behnken design.

The objective of this research was to develop a novel adsorbent to eliminate mercury (Hg(II)) from water. A unique citrate-crosslinked La-MOF/citrate crosslinked chitosan composite sponge (La-MOF@CSC composite sponge) was successfully synthesized in an acidic environment using a one-step technique. Modifying the composition of adsorbent materials is a commonly employed strategy to enhance adsorption capacity, particularly for materials composed of metal-organic frameworks.

Immobilization of biomolecular anthocyanin natural sensor into plasma-cured polyethylene terephthalate fibers from recycled plastic waste for determination of ammonia.

Polyester textiles have been applied in numerous industrial applications. Polyester fibers are characterized with being excellent insulators to electricity, having excellent flexural and impact strength, ease of manufacture, low-cost, as well as having resistance to moisture and chemicals. However, polyester fibers cannot be stained due to the absence of active dyeing sites on the surface of the fibrous structure.

Development of photoluminescent viscose fibers integrated with polymer containing lanthanide-doped phosphor.

Smart clothing refers to textiles that can sense an external stimulus by changing their physical properties such as colorimetric and fluorescent fabrics. The pad-dry-curing coloration approach was used to apply a luminous and hydrophobic composite coating onto cellulose-based materials. This novel method includes incorporating phosphor nanoparticles made from lanthanide-doped strontium aluminum oxide (LSAO) into room temperature vulcanizing silicone rubber (RTV).

Efficient Removal of Deltamethrin from Aqueous Solutions Using a Novel Lanthanum Metal-Organic Framework: Adsorption Models and Optimization via Box-Behnken Design.

Eliminating pesticides is essential for lowering the dangers to our environment. To do this effectively, it is crucial to find adsorbents with remarkable adsorption capacities, easy retrieval, and separation. Metal-organic frameworks (MOFs) have been extensively recognized for their exceptional ability to absorb pollutants.

Application of Metal-Organic Frameworks for Efficient Removal of Doxorubicin Hydrochloride: Removal Process Optimization and Biological Activity.

This study looked at the doxorubicin hydrochloride (DOX) anticancer drug's adsorption characteristics on a silver-based metal-organic framework (Ag-MOF). X-ray diffraction (XRD), scanning electron microscopy (SEM), and X-ray photoelectron spectroscopy (XPS) were used for the characterization of Ag-MOF. The pore volume and surface area of Ag-MOF were determined through Brunauer-Emmett-Teller (BET) testing at 77 K to be 0.

Electrospun glass nanofibers to strengthen polycarbonate plastic glass toward photoluminescent smart materials.

Electrospun glass nanofibers (GNFs) were used to strengthen polycarbonate (PC) to create long-persistent photoluminescent and fluorescent smart materials such as afterglow concrete and smart window. Physical integration of lanthanide-activated aluminate (LA) nanoparticles (NPs) yielded transparent GNFs@PC smart sheets. Spectral investigations utilizing photoluminescence and CIE Lab parameters were performed to confirm that the translucent appearance of GNFs@PC changed to green when exposed to UV light.

Novel Iron Oxide Nanoparticle-Fortified Carbon Paste Electrode for the Sensitive Voltammetric Determination of Atomoxetine.

Herein, the fabrication and full characterization of a novel atomoxetine (ATX) voltammetric carbon paste electrode (CPE) fortified with iron oxide nanoparticles (FeONPs) is demonstrated. Modification of the carbon paste matrix with the metallic oxide nanostructure provides proper electrocatalytic activity against the oxidation of ATX molecules at the carbon paste surface, resulting in a noticeable improvement in the performance of the sensor. At the recommended pH value, ATX recorded an irreversible anodic peak at 1.

Multifunctional Lipophobic Polymer Dots from Cyclodextrin: Antimicrobial/Anticancer Laborers and Silver Ions Chemo-Sensor.

β-Cyclodextrin (CD) is currently exploited for the implantation of lipophobic polymer dots (PDs) for antimicrobial and anticancer laborers. Moreover, the PDs were investigated to act as a chemo-sensor for metal detection. The data revealed that under basic conditions, photoluminescent PDs (5.

Copper(I)-catalysed synthesis of symmetrical perfluoroterphenyl analogues; fluorescence, antioxidant and molecular docking studies.

Pentafluoroaryl analogues have been found to exhibit para specific nucleophilic aromatic substitution (S Ar). Herein, we describe the use of S Ar chemistry to create luminous perfluorinated symmetrical terphenyls. Both of S Ar chemistry and copper(I)-catalysed decarboxylative cross-coupling were applied for the synthesis of the perfluorinated symmetrical terphenyls in high yields from the corresponding derivatives of aryl iodide and potassium salt of fluorobenzoate.