Publications by authors named "Naseer Uddin"

This case report delineates the complex management of a 65-year-old female with established diabetes, hypertension, and ischemic heart disease, who presented with refractory angina despite comprehensive medical management. Coronary angiography identified significant pathology in the right coronary artery alongside a previously placed, functioning stent in the left anterior descending artery. The intervention was complicated by the occurrence of a type B coronary artery dissection and a type III coronary perforation during an attempt to extract a stent.

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  • Pulmonary arterial hypertension (PAH) is characterized by the narrowing of blood vessels in the lungs, and Sotatercept is a new treatment showing promise for patients with this condition.
  • A meta-analysis of two randomized controlled trials, involving 429 patients, found that Sotatercept significantly improved walking distance, functional ability, and reduced pulmonary vascular resistance compared to placebo.
  • While Sotatercept did not show a statistically significant effect on NT-proBNP levels, further studies are needed to determine the clinical importance of these results.
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Background: The popularity of e-cigarettes has risen dramatically over the last few years, particularly among the younger population. Although the use of combustible cigarettes has established evidence to be associated with the development of several adverse cardiopulmonary diseases, the investigations regarding the prospective long-term effects of e-cigarette use on the cardiovascular system have just begun. We set to investigate if there is an association between the history of MI and e-cigarette use among smokers and non-smokers?

Methods: The current review aims to assess the association of myocardial infarction with e-cigarette consumption.

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  • High-Density Lipoprotein Cholesterol (HDL-C) has traditionally been viewed as protective against cardiovascular disease (CVD), with higher levels suggesting lower risk.
  • Recent research indicates that extremely high HDL-C levels may actually be linked to increased CVD risks, challenging the idea that higher is always better.
  • The relationship between HDL-C, genetics, and cardiovascular outcomes is complex, necessitating further studies to understand how HDL-C levels influence CVD risk and guide treatment approaches.*
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  • Bempedoic acid (BA) is a new lipid-lowering medication showing effectiveness in reducing cardiovascular risks in high-risk patients, based on a review of seven randomized controlled trials with over 17,000 participants.
  • The studies demonstrated that BA significantly reduces the occurrence of major adverse cardiovascular events and lowers levels of LDL cholesterol and total cholesterol compared to a placebo.
  • However, BA is associated with increased risks of gout, hyperuricemia, and worsening renal function, making it a potential option for patients who cannot tolerate statins or require extra lipid-lowering therapy.
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Monkeypox (MPX) is a zoonotic disease caused by the MPX virus from the poxviridae family of orthopoxviruses. Typically, endemic in central and west Africa, it has now become a matter of concern since cases have been reported in non-endemic countries around mid-June 2022, especially in the European region, with the transmission not related to travel. The diagnosis is made by PCR testing of the skin lesions.

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