New insight into the effect of lycopene on the oxidative stress in acute kidney injury.

Objective: To evaluate the nephroprotective effect of lycopene (LPN) in acute kidney injury (AKI) regarding the oxidative stress (OS).

Materials And Methods: Thirty Sprague Dawley male rats were divided into three groups - control group: rats treated with distilled water (orally) for 10 days ( = 10); AKI group: rats treated with distilled water and diclofenac (intraperitoneal) for 10 days ( = 10); treated group: rats treated with LPN (orally) and diclofenac for 10 days ( = 10). Body mass index (BMI) and estimated glomerular filtration rate (eGFR) were measured.