Feeding injury of major lepidopteran soybean pests in South America.

Lepidopteran pests are major factors limiting soybean productivity in South America. In some cases, effective management of these species requires the use of foliar insecticides. For sustainable use of these insecticides, they should only be applied when insect population size exceeds an economic threshold.

Eugenia gracillima essential oil has pharmaceutical applications in pain and inflammation without toxic effects in mice.

Ethnopharmacological Relevance: Eugenia gracillima is widely used by the population in the manufacture of pulps and jellies, with popular reports of its use in the treatment of infections in the urinary system, respiratory and dermatological problems. A previous study reports that EO from E. gracillima leaves proved to be a promising antioxidant agent in combating the promastigote forms of protozoa.

Acute and Reproductive Toxicity Evaluation of Ormona SI and Ormona RC-Two New Nutraceuticals with Geranylgeraniol, Tocotrienols, Anthocyanins, and Isoflavones-In Adult Zebrafish.

The zebrafish is a popular organism to test the toxicity of compounds. Here, we evaluate the acute and reproductive toxicity of Ormona SI (OSI) and RC (ORC), two herbal products developed for menopausal women with tocotrienols, geranylgeraniol, isoflavones, and anthocyanins. The acute toxicity was evaluated by behavioral alterations, lethality, and tissue changes (intestine, liver, kidney) after oral treatment with high product doses (500, 1000, and 2000 mg/kg).

Retrospective Analysis of the SARS-CoV-2 Infection Profile in COVID-19 Positive Patients in Vitoria da Conquista, Northeast Brazil.

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is responsible for causing Coronavirus Disease-2019 (COVID-19), a heterogeneous clinical condition that manifests varying symptom severity according to the demographic profile of the studied population. While many studies have focused on the spread of COVID-19 in large urban centers in Brazil, few have evaluated medium or small cities in the Northeast region. The aims of this study were: (i) to identify risk factors for mortality from SARS-CoV-2 infection, (ii) to evaluate the gene expression patterns of key immune response pathways using nasopharyngeal swabs of COVID-19 patients, and (iii) to identify the circulating SARS-CoV-2 variants in the residents of a medium-sized city in Northeast Brazil.

A New Recombinant Multiepitope Chimeric Protein of Is a Promising Marker for the Serodiagnosis of Leptospirosis.

The zoonotic disease leptospirosis is caused by pathogenic species of the genus and was recently included in the list of Neglected Diseases by the World Health Organization. Leptospirosis burden is estimated to have over a million human cases and cause 60 thousand deaths annually, in addition to its economic impact and veterinary concern. The microscopic agglutination test (MAT), recommended by the World Health Organization, exhibits reduced sensitivity at the beginning of the disease, in addition to being technically difficult.

Prospecting antibacterial activity of a peptide from trypsin inhibitor isolated from tamarind seed.

Bacterial infections have become a global concern, stimulating the growing demand for natural and biologically safe therapeutic agents with antibacterial action. This study was evaluated the genotoxicity of the trypsin inhibitor isolated from tamarind seeds (TTI) and the antibacterial effect of TTI theoric model, number 56, and conformation number 287 (TTIp 56/287) and derived peptides . TTI (0.

Structural Prediction and Characterization of (ConGF) Lectin Complexed with MMP1: Unveiling the Antiglioma Potential of Legume Lectins.

A glioblastoma (GBM) is a highly malignant primary brain tumor with a poor prognosis because of its invasiveness and high resistance to current therapies. In GBMs, abnormal glycosylation patterns are associated with malignancy, which allows for the use of lectins as tools for recognition and therapy. More specifically, lectins can interact with glycan structures found on the malignant cell surface.

Sensing performances of spinel ferrites MFeO (M = Mg, Ni, Co, Mn, Cu and Zn) based electrochemical sensors: A review.

The history of ferrites comes from many centuries and was fundamental in many fields. Initially, ferrites were extracted directly from nature, but in the last century, scientists learned to produce ferrites with different properties that gave origin to many advances in industrial and instrumental applications. More recently, the designed preparation of ferrites with nanometric size revealed remarkable characteristics.

Pathological Features in Paediatric Patients with TK2 Deficiency.

Thymidine kinase (TK2) deficiency causes mitochondrial DNA depletion syndrome. We aimed to report the clinical, biochemical, genetic, histopathological, and ultrastructural features of a cohort of paediatric patients with TK2 deficiency. Mitochondrial DNA was isolated from muscle biopsies to assess depletions and deletions.

Is there a similarity between the 2019 and 2022 oil spills that occurred on the coast of Ceará (Northeast Brazil)? An analysis based on forensic environmental geochemistry.

The main objective of this study was to investigate the 2019 and 2022 oil spill events that occurred off the coast of the State of Ceará, Northeastern Brazil. To further assess these mysterious oil spills, we investigated whether the oils stranded on the beaches of Ceará in 2019 and 2022 had the same origin, whether their compositional differences were due to weathering processes, and whether the materials from both were natural or industrially processed. We collected oil samples in October 2019 and January 2022, soon after their appearance on the beaches.

Increased oyster aquaculture in the Sado Estuary (Portugal): How to ensure ecosystem sustainability?

Aquaculture is one of the fastest growing sectors in the world. However, this may come with a cost, as increasing aquatic production is likely to impose changes in the environment. To ensure ecosystem sustainability, it is essential to think on this larger scale.

Onco-hematological patient care in times of COVID-19: a scoping review.

Objective: to identify and map health care aimed at onco-hematological patients in times of Coronavirus 2019.

Methods: this is a scoping review, anchored in the Joanna Briggs Institute theoretical framework, registered in the Open Science Framework, with searches carried out in June 2021, through searches in the databases.

Results: a final sample consisting of 20 articles was obtained, with emphasis on general care, treatment and stem cell donation.

K-Bessel regression model for speckled data.

Synthetic aperture radar (SAR) provides an efficient way to monitor the Earth's surface. But the speckle noise that the SAR system generates when acquiring images makes it difficult to understand and interpret SAR intensity features. To automatically analyze SAR images, this paper presents a K-Bessel regression (KBR) model in which a function of the mean intensity response is explained by other features (or covariates) determined in parallel.

Synthesis, in vitro schistosomicidal activity and ultrastructural alterations caused by thiosemicarbazones and thiazolidinones against juvenile and adult Schistosoma mansoni worms (Sambon, 1907).

Schistosomiasis is a neglected disease that affects about 258 million people worldwide. Caused by Schistosoma mansoni, helminth which, in Brazil, it is present on 19 states and capital. Praziquantel (PZQ) treatment presents low efficacy and adverse effects in parasites juvenile stages.

Dynamics diagnosis of the COVID-19 deaths using the Pearson diagram.

The pandemic COVID-19 brings with it the need for studies and tools to help those in charge make decisions. Working with classical time series methods such as ARIMA and SARIMA has shown promising results in the first studies of COVID-19. We advance in this branch by proposing a risk factor map induced by the well-known Pearson diagram based on multivariate kurtosis and skewness measures to analyze the dynamics of deaths from COVID-19.

Extended treatment with (1→3)(1→6)-β-d-glucan (Botryosphaeran) reduces obesity and its comorbidities in high-fat/high-sugar diet-fed rats.

Obesity is associated with other diseases such as diabetes and cancer. Botryosphaeran, a fungal (1→3)(1→6)-β-d-glucan, is described to present antimutagenic, hypoglycemic, hypocholesterolemic, and antitumor activities when administered by gavage over 15 days in rats and mice. Thus, the present study aims to analyze the metabolic effects of Botryosphaeran (12 mg/kg body weight/day) treatment over 30 days in obese Wistar male rats.

Impact of sociodemographic factors and screening, diagnosis, and treatment strategies on colorectal cancer mortality in Brazil: A 20-year ecological study.

Colorectal cancer (CRC) caused 261,060 deaths in Brazil over a 20-year period, with a tendency to increase over time. This study aimed to verify the sociodemographic factors predicting higher mortality caused by CRC and survival rates. Moreover, we aimed to verify whether the performance of screening, diagnostic and treatment procedures had an impact on mortality.

Essential oil from the leaves of Eugenia pohliana DC. (Myrtaceae) alleviate nociception and acute inflammation in mice.

Eugenia pohliana DC.(Myrtaceae) is used in folk medicine by communities in Brazil. However, there are no reports on its biological activity.

Methodology for LoRa Gateway Placement Based on Bio-Inspired Algorithmsfor a Smart Campus in Wooded Area.

The Internet of Things (IoT) device scenario has several emerging technologies. Among them, Low-Power Wide-Area Networks (LPWANs) have proven to be efficient connections for smart devices. These devices communicate through gateways that exchange points with the central server.

Expanding the Phenotype of 8p23.1 Deletion Syndrome: Eight New Cases Resembling the Clinical Spectrum of 22q11.2 Microdeletion.

Objective: To report the effectiveness of early molecular diagnosis in the clinical management of rare diseases, presenting 8 patients with 8p23.1DS who have clinical features that overlap the phenotypic spectrum of 22q11.2DS.

Use of the term whole grain on the label of processed and ultra-processed foods based on cereals and pseudocereals in Brazil.

There has been an increasing consumption of processed and ultra-processed foods, accompanied by growing concerns about the relationship between diet quality and health. Whole-grain foods, composed of cereals and pseudocereals, are recommended as part of a healthy diet, and food labeling is an important tool for consumers to identify the presence of whole grains in packaged foods. This study aimed to analyze the use of the term whole grain on the label of processed and ultra-processed foods based on cereals and pseudocereals (amaranth, quinoa, and buckwheat) in Brazil.