Publications by authors named "Narumon Thantamnu"
Safety and immunogenicity of an inactivated recombinant Newcastle disease virus vaccine expressing SARS-CoV-2 spike: Interim results of a randomised, placebo-controlled, phase 1 trial.
EClinicalMedicine
March 2022
Background: Production of affordable coronavirus disease 2019 (COVID-19) vaccines in low- and middle-income countries is needed. NDV-HXP-S is an inactivated egg-based recombinant Newcastle disease virus vaccine expressing the spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It's being developed by public sector manufacturers in Thailand, Vietnam, and Brazil; herein are initial results from Thailand.
View Article and Find Full Text PDFSafety and Immunogenicity of an Inactivated Recombinant Newcastle Disease Virus Vaccine Expressing SARS-CoV-2 Spike: Interim Results of a Randomised, Placebo-Controlled, Phase 1/2 Trial.
medRxiv
September 2021
Background: Production of affordable coronavirus disease 2019 (COVID-19) vaccines in low- and middle-income countries is needed. NDV-HXP-S is an inactivated egg-based Newcastle disease virus vaccine expressing the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It's being developed in Thailand, Vietnam, and Brazil; herein are initial results from Thailand.
View Article and Find Full Text PDFBackgroud: Influenza viruses cause substantial morbidity, especially in older age groups. Thus, they are amongst high priority groups for routine vaccination. However, vaccine-induced immune responses and effectiveness were reported as relatively low.
View Article and Find Full Text PDFFood-borne Salmonella outbreak in a single hospital ward.
Southeast Asian J Trop Med Public Health
March 2014
In June 2012, an outbreak of Salmonella group C gastroenteritis occurred on a single hospital ward among 54.2% (13/24) of volunteers undergoing an unrelated clinical trial and among 14.3% (1/7) hospital ward worker.
View Article and Find Full Text PDF6-month evaluation of JinHuang Chinese herbal medicine study in asymptomatic HIV infected Thais.
Southeast Asian J Trop Med Public Health
June 2003
Article Synopsis
- Good results from an in vitro study on JinHuang, a Chinese herbal medicine, prompted an in vivo study to assess safety and efficacy in asymptomatic HIV-infected individuals.
- An open study involving 21 Thai volunteers (12 females, 9 males) took place, with participants taking JinHuang for 6 months, monitored closely for side effects.
- Reported side effects included increased bowel movements (81%) and changes in taste/smell (52%), but no serious adverse events were noted; however, there were no significant changes in viral load or CD4 count, though many participants felt improvements in quality of life.
Article Synopsis
- The study focused on understanding the role and commitment of volunteers in HIV vaccine trials, highlighting concerns about risk behaviors and volunteers’ expectations throughout the trial process.
- Conducted with 164 volunteers, the study found no increase in risky behavior, and a significant decrease in risky sexual practices over time, demonstrating positive behavioral changes among participants.
- Volunteers reported favorable outcomes from their involvement, including knowledge gain and positive social contributions, reflecting their overall beneficial expectations from participating in the vaccine trials.