Differences in Antipsychotic-Related Adverse Events in Adult, Pediatric, and Geriatric Populations.

In recent years, antipsychotic medications have increasingly been used in pediatric and geriatric populations, despite the fact that many of these drugs were approved based on clinical trials in adult patients only. Preliminary studies have shown that the "off-label" use of these drugs in pediatric and geriatric populations may result in adverse events not found in adults. In this study, we utilized the large-scale U.

Perspectives of Mobile Versus Fixed Mammography in Santa Clara County, California: A Focus Group Study.

Objective: Our aim was to examine underserved women's perceptions on mobile versus fixed mammography in Santa Clara, California through a focus group study.

Background:  Research has shown that medically underserved women have higher breast cancer mortality rates correlated with under-screening and a disproportional rate of late-stage diagnosis. The Community Health Partnership in Santa Clara County, California runs the Community Mammography Access Project (CMAP) that targets nearly 20,000 medically underserved women over the age of 40 in the county through the collaborative effort of an existing safety net of healthcare providers.

Retroperitoneal sarcomas.

Retroperitoneal sarcomas are a rare and highly malignant group of tumors. Because of their anatomical location, they often reach a large size before detection and are difficult to diagnose clinically because of nonspecific symptoms. After surgical resection, the tumors display a high rate of recurrence, thus requiring long-term and often indefinite follow-up.

Cost-effectiveness of genetic testing in family members of patients with long-QT syndrome.

Background: Family members of patients with established long-QT syndrome (LQTS) often lack definitive clinical findings, yet may have inherited an LQTS mutation and be at risk of sudden death. Genetic testing can identify mutations in 75% of patients with LQTS, but genetic testing of family members remains controversial.

Methods And Results: We used a Markov model to assess the cost-effectiveness of 3 strategies for treating an asymptomatic 10-year-old, first-degree relative of a patient with clinically evident LQTS.