High-resolution 3-D scanning electron microscopy (SEM) images of DOT polynucleotides (PN): Unique scaffold characteristics and potential applications in biomedicine.

Introduction: Polynucleotides (PN) are becoming more prominent in aesthetic medicine. However, the structural characteristics of PN have not been published and PN from different companies may have different structural characteristics. This study aimed to elucidate the structural attributes of DOT™ PN and distinguish differences with polydeoxyribonucleotides (PDRN) using high-resolution scanning electron microscopy (SEM) imaging.