Optimal timing for intermittent administration of parathyroid hormone (1-34) for distraction osteogenesis in rabbits.

Background: To date, the usefulness of parathyroid hormone [PTH (1-34)] in distraction osteogenesis has been reported in several studies. We aimed to determine the optimal timing of PTH (1-34) administration in a rabbit distraction osteogenesis model.

Methods: The lower hind leg of a Japanese white rabbit was externally fixed, and tibial osteotomy was performed.