Personalized image-based tumor growth prediction in a convection-diffusion-reaction model.

Inter-individual heterogeneity of tumors leads to non-effectiveness of unique therapy plans. This issue has caused a growing interest in the field of personalized medicine and its application in tumor growth evaluation. Accordingly, in this paper, a framework of personalized medicine is presented for growth prediction of brain glioma tumors.

Simulating glioblastoma growth consisting both visible and invisible parts of the tumor using a diffusion-reaction model followed by resection and radiotherapy.

Glioblastoma is known to be among one of the deadliest brain tumors in the world today. There have been major improvements in the detection of cancerous cells in the twenty-first century. However, the threshold of detection of these cancerous cells varies in different scanning techniques such as magnetic resonance imaging (MRI) and computed tomography (CT).