Barriers to participation in medical research from the perspective of researchers.

Background: The first step toward organizing research activities is to obtain a correct perception of available capabilities. This study was conducted to investigate the researchers' views about barriers affecting research activities.

Methods: This descriptive, cross-sectional study was conducted using the census method.

Anethole, a Medicinal Plant Compound, Decreases the Production of Pro-Inflammatory TNF-α and IL-1β in a Rat Model of LPS-Induced Periodontitis.

Periodontitis (PD) is known to be one of most prevalent worldwide chronic inflammatory diseases. There are several treatments including antibiotics for PD; however, since drug resistance is an increasing problem, new drugs particularly derived from plants with fewer side effects are required. The effects of trans-anethole on IL-1 β and TNF-α level in a rat model of PD were investigated and compared to ketoprofen.