Publications by authors named "Narges Azzam"
Article Synopsis
- The 4th iteration of the Chicago Classification (CC v4.0) introduced stricter criteria for diagnosing Ineffective Esophageal Motility (IEM), leading to fewer patients being classified with this condition compared to the previous version.
- A retrospective study analyzed high-resolution manometry data from 452 patients, revealing that 39% of those initially diagnosed with IEM were reclassified as having normal motility under the new criteria.
- Patients retaining the IEM diagnosis exhibited worse esophageal function and acid exposure, suggesting that the updated criteria provide a more clinically relevant understanding of IEM.
Background: Achalasia is characterized by aperistalsis with poor relaxation of the lower esophageal sphincter (LES). We aimed to systematically assess whether LES metrics on high-resolution manometry (HRM) correlate with the symptomatic or endoscopic presentation of patients with achalasia.
Methods: A retrospective study was performed at two tertiary medical centers.