Synopsis of recent research by authors named "Narges Abdali"
- Narges Abdali's research primarily focuses on the structural and functional characterization of multidrug efflux pumps in Gram-negative bacteria, particularly the AcrAB-TolC system, highlighting their role in antibiotic resistance.
- Abdali's investigations include molecular dynamics simulations and the discovery of efflux pump inhibitors (EPIs) that interact with the AcrA component, aiming to potentiate the efficacy of existing antibiotics and combat bacterial resistance.
- The research also extends to identifying pore-forming proteins in various pathogenic bacteria, providing insights into their cell wall composition and function, thereby contributing to a better understanding of bacterial resistance mechanisms.
