Evaluation of MMP-1, MMP-8, MMP-9 serum levels in patients with adrenal tumors prior to and after surgery.

The aim of the study is to evaluate MMP-1, MMP-8 and MMP-9 serum levels in patients with adrenal tumors prior to and after surgery. Metalloproteinase-1 (MMP-1), MMP-8 and MMP-9 serum levels were evaluated in 43 patients operated on at our clinic between 1997-1999. Forty-one (95.

Colorectal carcinoid tumors--own experience.

Symptomatology, diagnostics and treatment problems in 5 patients with colorectal carcinoid are presented. From 1974 to 1999 in the Clinic of Endocrinological and General Surgery of the Medical University of Lódź, 3001 patients underwent surgery due to acute appendicitis and 431 for colorectal cancer. Among them, there were 5 patients in whom the histological examination revealed colorectal carcinoid.

Medullary thyroid carcinoma (MTC)--clinical and molecular aspects on the basis of own experience.

In our clinic 19615 patients were operated over 25 years on for goiter. Malignant thyroid neoplasms were found in 1049 (5.3%) patients including 875 (83.

Thyroid cryotherapy in an experimental rat model-topography of temperature during therapy and functional results.

The aim of this study was to investigate post cryotherapy thyroid function status of normal rat thyroid tissue and to determine the topography of temperature of cryotreated tissues and of tissues adjacent to them. Nitrous oxide cryotherapy was performed in 40 male Wistar rats. They were divided into four groups of 10.

Pregnancy following operative and complementary treatment of thyroid cancer.

In 1974-1998, 18,602 patients were operated on due to goitre, including 16,575 (89.1%) women and 2,027 (10.9%) men.

[The diagnosis and operative treatment of solitary thyroid nodule: a prospective study].

The aim of the paper is to evaluate the usefulness of pre- and intraoperative examination methods in the diagnostics of solitary thyroid nodules, as well as the assessment of the histologic structure of these nodules. From 1.12.

[Treatment of solitary toxic thyroid nodules with the use of percutaneous ethanol injections].

Twenty women aged 18-76 years (mean 42 +/- 23 years) with solitary benign toxic thyroid nodule were treated with intranodular percutaneous 96%-ethanol injection, performed under ultrasound guidance. 1 ml of ethanol was instilled per 1 cm3 of nodule tissue. 2-5 (mean 3.

Vascular endothelial growth factor and basic fibroblast growth factor evaluation in blood serum of patients with hormonally active and inactive adrenal gland tumours.

The vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) levels of 36 patients with adrenal gland tumours were analysed. The mean age of patients was 43 years (29-67 years), and there were 25 women (69.4%) and 11 men (31.

[The treatment of solitary thyroid nodules in non-toxic goiter with 96% ethanol injections].

40 patients (39 women and 1 man) aged 13-66 years (mean 35.9 years) with solitary benign non-toxic thyroid nodule confirmed by clinical and hormonal examination, ultrasonography and fine needle aspiration biopsy, were treated with intranodular percutaneous 96% ethanol injection, performed under ultrasound guidance. There were 34 patients with solid nodule (including 4 patients) with solitary nodule in recurrent goitre after thyroidectomy) and 6 patients with cyst.

The surgical treatment of adrenal gland tumors--incidentaloma.

Analysis of 32 patients operated on because of accidentally discovered adrenal tumors "incidentaloma" is presented. In 12 of them there was subclinical hormonal activity, in 9 of them tumors turned out to be pheochromocytoma and 3 of them were cortex adenoma. There were 20 hormonally inactive tumors, in 5 of them there were malignant lesions (4 of the cortex and 1 of the medulla).

[About changes in the structure of surgically treated goiter].

On the base of our own goiter material treated surgically between 1974-1996, we compared incidence of various types of goiter and thyroid carcinoma in years 1974-1985 and 1986-1996. We stated statistically significant decrease of operated Basedow goiter and significant incidence increase of thyroid cancer. In given years frequency of incidence of differentiated and anaplastic thyroid carcinoma have been changed.

[Strumectomy in children and adolescents--personal studies with 12,000 operations].

At the Surgery Clinic of the Endocrinology Institute in Lódź we operated 12 344 patients between 1974 and 1992 because of various types of goitre. Among these there were 295 children and adolescents, 2.4%- aged between 9-18 years: 268 girls (90.

Ambient thermal conditions and thermoregulatory mechanisms in fever in rabbits.

At ambient temperatures 10 degrees C, 20 degrees C, 30 degrees C, and 40 degrees C the influence of heat dissipation on the thermoregulatory mechanisms in rabbits with fever was investigated. Temperature of the brain (TBr-accuracy +/- 0.05 degree C) temperature of the nasal mucosa (TN) and temperature of the ear pinna (TAU-accuracy +/- 0.

Absence of selective brain cooling in pyrogen-induced fever in rabbits.

In 9 rabbits the effect of intravenous administration of E. coli pyrogen 0.5 microgram/kg on the reaction of selective brain cooling was studied at ambient temperatures of 20, 30 and 40 degrees C.

Human brain homeothermy during sleep and wakefulness: an experimental and comparative approach.

To date human brain temperature has not been measured exactly. Limited published data indicate it to be about 37.5 degrees centigrade, which surprisingly is 1.

Reversible brain hyperthermia during audiogenic seizures in rats.

Reversible brain hyperthermia during audiogenic seizures in rats. Acta Physiol. Pol.

[Usefulness of a strain of mice with genetically determined audiogenic epilepsy as a model of experimental epilepsy].

Behavioural and bioelectric characteristics of epileptic seizures caused by acoustic stimulus in mice from the Swiss Albino Rb strain with genetically determined audiogenic epilepsy are presented. The value of this epilepsy model is emphasized stressing that the epileptogenic stimulus acts from a distance, causing no damage to the nervous system and no artifacts. Besides that, seizures can be provoked at a definite frequency and at arbitrarily chosen time.

Significance of cranial circulation for the brain homeothermia in rabbits. II. The role of the cranial venous lakes in the defence against hyperthermia.

Chronic experiments were conducted on five freely moving rabbits at ambient temperatures of 0-42 degrees Celsius. The influence of nasal mucosal thermal changes on the venous blood temperature inside the pterygoid plexus and on the temperatures at three intracerebral sites were investigated against the background of the carotid arterial blood temperature shifts. A correlation was found between: (i) the fluctuations in the nasal mucosal temperature reflecting its vasomotor responses, (ii) temperature shifts of the pterygoid plexus venous blood, and (iii) of the ventral brain.

Significance of cranial circulation for the brain homeothermia in rabbits. I. The brain-arterial blood temperature gradient.

The hypothalamic-arterial blood temperature gradient (THpr-TAC difference) was studied on 10 freely moving rabbits at ambient temperatures between 0 and 42 degrees Celsius. In cold environment, below 10 degrees Celsius the THpt-TAC gradient varied considerably, but some distinct correlations were found between vasomotor responses of the nasal mucosa and fluctuations of brain temperature, as well as between vasomotor responses of the ear pinnas and changes of the arterial blood temperature. Vasodilatation of the nasal mucosa or the ear pinna caused respectively a drop in brain temperature or in arterial blood temperature.