Postoperative Outcomes in Condylar Hyperplasia: Proportional Condylectomy Versus Orthognathic Surgery.

The management of patients with facial asymmetry caused by condylar hyperplasia remains a subject of ongoing debate. This study compared active patients with unilateral condylar hyperplasia (UCH) who underwent proportional condylectomy with ceased patients with UCH who underwent orthognathic surgery, evaluating esthetics, function, and satisfaction. The retrospective study included 2 groups: group A, with 15 active patients with UCH who underwent proportional condylectomy, and group B, with 22 ceased patients with UCH who underwent orthognathic surgery.

Adsorption and release pattern of recombinant human bone morphogenic proatin 2 onto different bone grafts and its consequent osteoblasts` activation and neutrophils` priming.

Objectives: Controlled long-term delivery of recombinant human bone morphogenic proatin 2 (rhBMP2) eluted in a collagen scaffolds suffer from only a high initial burst release. The purpose of the current study was to investigate the long-term delivery of rhBMP2 when mixed with different bone grafts and its impact on osteoblastic activity and neutrophil priming.

Methods: rhBMP2 was separately mixed with xenograft, allograft, or alloplast and incubated for 30 days.

The Effect of Implant-Associated Factors on the Long-Term Outcomes of Dental Implants.

The long-term outcomes of dental implants are influenced by a variety of factors, all of which play critical roles in their stability, functionality, and esthetic appeal. This review focuses on several key characteristics of dental implants that impact their success overtime: dimensional, morphologic, material, osseointegrative, and connective/prosthetic characteristics. This article synthesizes current literature to analyze how these factors influence the long-term success of dental implants, emphasizing the need for a comprehensive approach in implant selection and placement.

Long-Term Survival of Dental Implants in Irradiated Patients.

The surgical ablation of head and neck cancer followed by radiotherapy often leads to unfavorable functional and aesthetic outcomes. Studies have demonstrated that these outcomes can significantly impact quality of life. Dental implants play a crucial role in rehabilitation by facilitating the use of suprastructures and obturators.

Effect of Orthognathic Surgery on Pre-existing Temporomandibular Disorders.

The management of patients with pre-existing temporomandibular disorders (TMDs) undergoing orthognathic surgery remains a subject of ongoing debate. This study aimed to profile these individuals and evaluate the correlation between orthognathic surgery and alterations in TMD indicators and symptoms. We conducted a retrospective cohort investigation involving patients with skeletal malocclusion and established TMDs.

Increased Prevalence of Generalized Joint Hypermobility Observed in Patients With Recurrent Temporomandibular Joint Dislocation.

Background: Generalized joint hypermobility (GJH), determined by the Beighton score, is a fundamental part of diagnosing benign joint hypermobility syndrome (BJHS), which may also present extra-articular manifestations, and is determined by the Brighton criteria.

Purpose: This study was designed to investigate whether there is an association between recurrent temporomandibular joint (TMJ) dislocation and these disorders.

Study Design, Setting, And Sample: A retrospective cross-sectional study was conducted.

"Proportional Condylectomy" for Vertical Condylar Hyperplasia Without Intermaxillary Elastics: Clinical Results and Patient Satisfaction.

Objectives: First, to investigate the clinical outcome of 'proportional condylectomy' for patients with active unilateral condylar hyperplasia without complementary treatment by intermaxillary elastics and, second, to examine their level of satisfaction regarding function and esthetics.

Study Design: A retrospective observational descriptive study was conducted. All patients included in the study suffered from active unilateral condylar hyperplasia with a vertical component.

Are There Cephalometric Measurements Associated With Recurrent Temporomandibular Joint Dislocation?

Purpose: Several theories have been proposed for the etiology of recurrent temporomandibular joint (TMJ) dislocation. The purpose of the present study was to determine whether there are cephalometric measurements associated with this phenomenon.

Methods: A retrospective case-control study was performed, which included individuals who suffered from recurrent TMJ dislocation and a control group composed of patients who suffered from unrelated odontogenic infections and did not have any TMJ disorder.

Explant Modeling of the Immune Environment of Head and Neck Cancer.

Patients exhibit distinct responses to immunotherapies that are thought to be linked to their tumor immune environment. However, wide variations in outcomes are also observed in patients with matched baseline tumor environments, indicating that the biological response to treatment is not currently predictable using a snapshot analysis. To investigate the relationship between the immune environment of tumors and the biological response to immunotherapies, we characterized four murine head and neck squamous cell carcinoma (HNSCC) models on two genetic backgrounds.

A platform for locoregional T-cell immunotherapy to control HNSCC recurrence following tumor resection.

Surgical resection of head and neck squamous-cell carcinoma (HNSCC) is associated with high rates of local and distant recurrence, partially mitigated by adjuvant therapy. A pre-existing immune response in the patient's tumor is associated with better outcomes following treatment with conventional therapies, but improved options are needed for patients with poor anti-tumor immunity. We hypothesized that local delivery of tumor antigen-specific T-cells into the resection cavity following surgery would direct T-cells to residual antigens in the margins and draining lymphatics and present a platform for T-cell-targeted immunotherapy.

The influence of mandibular condyle morphology on TMJ anterior dislocations.

Objectives: The present study was designed to investigate the correlation between the bony morphology of the mandibular condyle and the occurrence of temporomandibular joint (TMJ) idiopathic anterior dislocation.

Study Design: A comparative retrospective study was conducted among 14 patients presenting idiopathic anterior dislocations (study group) and 15 patients who did not suffer from any TMJ disorders (control group). All patients underwent a multidetector computed tomography scan demonstrating the full extent of their joints.

The efficacy of a protective protocol for oral and maxillofacial surgery procedures in a COVID-19 pandemic area-results from 1471 patients.

Objective: To examine the effectiveness of an empiric protection protocol during oral surgical treatments in a COVID-19 pandemic area and to evaluate the potential effect of postponed dental procedures on the frequency of facial infections during a lockdown period.

Methods: We performed a retrospective analysis of a case series of a broad-spectrum of oral surgeries in a COVID-19 pandemic area. Data collection included patient age, type of procedure performed, and COVID-19 status of staff and patients.

The influence of articular eminence morphology on temporomandibular joint anterior dislocations.

Objective: The aim of this study was to investigate the correlation between the bony morphology of the articular eminence and the occurrence of idiopathic anterior temporomandibular joint (TMJ) dislocation.

Study Design: A comparative retrospective study was conducted in 14 patients with idiopathic anterior dislocations (study group) and 14 patients who did not suffer from any TMJ disorders (control group). All patients underwent multidetector computed tomography (MDCT), which demonstrated the full extent of their joints.

Nonfixated inlay graft for anterior localized mandibular defect.

Localized vertical bone defects within the anterior mandibular alveolar ridge frequently pose a unique challenge for functionally and aesthetically pleasing rehabilitation of this area. Causes for significant bone loss in this region may include periodontal disease, postextraction atrophy, trauma, and orthodontic treatment. In the presence of such a defect, ridge augmentation may be obligatory before installation of dental implants.

Vertical Alveolar Augmentation Using BMP-2/ACS/Allograft with Printed Titanium Shells to Establish an Early Vascular Scaffold.

Traditional reconstruction of major alveolar ridge deficiency has required autogenous cortical cancellous particulate bone grafts, often augmented with particulate allogeneic components. Now there is a new concept to consider, that of orthoalveolar form. This paradigm shift involves components of the tissue engineering triad of inductive growth factors combined with a matrix and stem cells, together with osteotomies or devices designed for space maintenance.

Computerized Navigation for Minimal Invasive Retrieval of Displaced Dental Implants in the Lower Jaw.

Displaced dental implants in the mandible may constitute a clinical challenge for both physicians and patients. The complex anatomy of the floor of the mouth, together with its subsequent violation due to implant displacement makes implant allocation and retrieval a challenging procedure. Computerized navigation surgery (CNS) has been previously described and proved successful in various surgical modalities.

Indirect Bactericidal Properties of Recombinant Human Bone Morphogenetic Protein 2 In Vitro.

Purpose: Bone morphogenetic proteins (BMPs) are secreted cytokines and are involved in various metabolic functions and inflammatory processes in different organs. The purpose of this study was to investigate whether BMPs also possess antimicrobial properties in direct or indirect ways.

Materials And Methods: Antibacterial properties of recombinant human BMP2 (rhBMP2) were tested on 4 bacteria species (Staphylococcus aureus, Escherichia coli, Streptococcus mitis, Streptococcus constellatus) to examine the potential synergism of rhBMP2 with antibiotics.

Successful Mandibular Mucormycosis Treatment in the Severely Neutropenic Patient.

Purpose: Mucormycosis is a rare opportunistic and aggressive deep fungal infection that predominantly affects immunocompromised patients, and its mortality rate has been reported as up to 80%. Typing of the infection is based mainly on clinical and anatomic presentations, with the most common being the rhinocerebral type.

Materials And Methods: This report presents 3 patients with cancer who had successful treatment of mandibular mucormycosis.

Release of Irretrievable Abutment Healing Caps Using Cooling: Proof of Concept and Clinical Recommendations.

Purpose: To study the relation between irretrievable abutment healing caps (AHCs), temperature, and the torque required to remove the AHCs from implants.

Materials And Methods: Twenty implants, 13 mm long and 4.2 mm in diameter, were inserted into four acrylic boxes and covered with acrylic resin.

Four-years' experience with dynamic implants with internal port for minimally invasive sinus elevation.

Objective: The purpose of this article is to describe long-term results of the dynamic implant valve approach (DIVA) for the dental implant procedures when the implant system with internal ports was used.

Method And Materials: During 2012 to 2015, 378 titanium-aluminum-vanadium implants (Ti6Al4V ELI; diameter 3.75 mm; length 11.

Imperforate titanium shell enclosing recombinant human bone morphogenetic protein-2-induced bone formation for high-profile dental implants in rabbit tibia.

Purpose: To evaluate the use of a nonperforated titanium occlusive device over high-profile dental implants in rabbit tibia using recombinant human bone morphogenetic protein-2 (rhBMP-2) in an absorbable collagen sponge (ACS) for augmentation grafting.

Materials And Methods: Eight New Zealand white rabbits were used for the experiment. All rabbits underwent computed tomography of the right tibia.