Publications by authors named "Nardi A"

Background/objectives: This study aimed to determine the percentage and duration of neutralizing antibodies against the Omicron variant in human milk after vaccination against SARS-CoV-2, considering the three different vaccine technologies approved in Brazil.

Methods: A cross-sectional study was conducted with lactating women who received the complete vaccination cycle with available vaccines (AstraZeneca, Pfizer, CoronaVac, and Janssen). The participants resided in Rio de Janeiro, and samples were collected from April to October 2022.

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Background: Genitourinary health significantly affects the quality of life of men, particularly those in middle age. Recent studies have shown that more than half of the men aged over 40 years experience some degree of low urinary tract symptoms (LUTS) or erectile dysfunction (ED).

Objective: To assess the prevalence of ED and LUTS in middle-aged men and correlate this with quality of life data.

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The charge transfer (CT) reactions in nucleic acids are crucial for genome damage and repair and nanoelectronics using DNA as a molecular conductor. Previous experimental and theoretical works underlined the significance of nucleic acid structural dynamics on CT kinetics, requiring models that incorporate the dynamics of the nucleic acid, solvents, and counterions. Here, we investigated hole transfer kinetics in poly adenine single and double strands at various temperatures and the rate enhancement due to adenine-to-7-deazaadenine mutation by means of a QM/MM approach.

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Background: The offspring of parents with bipolar disorder (BD) and with attention deficit hyperactivity disorder (ADHD) have a higher risk of having the same condition. Both disorders also share psychopathological symptoms; however, little is known about their genetic overlap. To examine whether the offspring of parents with BD have a greater chance of being affected by ADHD, we conducted a systematic review.

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Objectives: Thus, through a narrative review, this article analyzes how the advancement of technology, the use of digital resources, and social media have impacted the doctor-patient relationship.

Methods: We conducted a scoping review on the relationship between Digital Health Equity and Telemedicine and e-health via Scopus and Pubmed electronic databases. The following inclusion criteria were established: papers on the relationship between digital health equity and telemedicine and e-health, written in English and with no time limits.

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The current study presents the case of a young man with intellectual disability related to fetal alcohol syndrome, referred for forensic psychiatric examination of criminal liability following charges of armed robbery, and who was considered not criminally liable. In such cases, it is crucial to perform early diagnosis and rely on educational and developmental services and a supportive home environment to decrease complications such as substance use and criminal involvement.

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Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals known for their persistence and bioaccumulation, leading to widespread environmental contamination. Despite their recognised environmental risks, particularly to aquatic wildlife, including marine invertebrates, detailed impact studies are limited. PFAS can be categorised according to the length of the compound chain, with short-chain PFAS announced as a safer alternative to the more commonly used long-chain PFAS.

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Background: Bipolar disorder (BD) presents with a wide range of symptoms that vary among relatives, casting doubt on categorical illness models. To address this uncertainty, we investigated the heritability and genetic relationships between categorical and dimensional models of BD in a family sample.

Methods: This retrospective study included participants (n = 397 Females, n = 329 Males, mean age 47 yr) in the Amish-Mennonite Bipolar Genetics (AMBiGen) study from North and South America that were assigned categorical mood disorder diagnoses ("narrow" or "broad") by structured psychiatric interview and completed the Mood Disorder Questionnaire (MDQ), which assesses lifetime history of manic symptoms and associated impairment.

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Article Synopsis
  • The European Union is promoting research in healthy aging, particularly through the use of advanced technologies like virtual reality (VR) for cognitive rehabilitation in older adults with Mild Cognitive Impairment (MCI).
  • A randomized controlled clinical study will include 30 participants aged 65 and older, evaluating the feasibility and effectiveness of a 3-month immersive VR cognitive remediation program, supervised by health professionals.
  • The study will measure outcomes such as quality of life, cognitive functions, and mental health indicators to determine the program's impact on participants.
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Ninety years after his death in 1934, the artistic beauty of the innovative brain images created by physician and histologist Santiago Ramón y Cajal, as well as his revolutionary neuroanatomical theory, remains relevant today. As a scientist who isolated brain nerve cells, he visualized them as physically distinct entities, answering one of the most crucial questions of his time. Prior to his work, the prevailing belief was in the reticular theory, which suggested that nervous tissue was continuous and formed a network of interconnected cells.

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Article Synopsis
  • The study investigates the quality of online information about anxiety treatment in English and Italian websites, assessing factors like scientific quality, readability, and technological aspects.
  • A systematic search was conducted, evaluating 78 Italian and 60 English websites, revealing that English sites generally offered better quality information and higher technological standards, but both were challenging to read.
  • The findings suggest the need for improved online health resources to ensure users can access comprehensive and understandable information about anxiety treatment options.
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Article Synopsis
  • Social anxiety disorder (SAD) is a common yet often overlooked condition that can severely impact various aspects of a person's life, highlighting the need for tailored treatment guidelines, particularly in Brazil.
  • A systematic review analyzed various treatment options for SAD, identifying selective serotonin reuptake inhibitors (SSRIs) as the preferred medication, with cognitive behavioral therapy (CBT) recognized as the top psychological intervention.
  • The study emphasizes the importance of considering factors like access to treatments, adherence, response rates, and side effects in selecting the most effective SAD treatment for patients in Brazil.
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This research describes incorporating the principles of the United Nations Convention on the Rights of Persons with Disabilities (CRPD) in training students at an Italian university. It also describes the perception of students on the rights of people with disabilities and the quality of services using the questionnaire the Well-Being at Work and Respect Right (WWRR), the objective is to compare the responses of students from the faculty of health sciences and health professionals human rights respect, organizational well-being, and job satisfaction in healthcare environments method: Cross-sectional study the data obtained were analyzed using the ANOVA test and Chi-SQUARE test results: University students have little recognition of the professional roles for the social and labor inclusion of users of health services, which promotes rethinking the type of training they receive conclusions: the findings show the need to incorporate in a more detailed way the principles of the CRPD in university training plans that promote an emphasis on disabilities based on human rights, despite the fact that the perception by students is optimistic in relation to respect for the rights of users in health services where they have done their training or practices, these results indicate a reevaluation of university training that gives a balance between technical skills but with an emphasis on human rights and social inclusion in health services.

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Introduction: Female sexual dysfunction (FSD) remains a silent problem, especially in Arabic-speaking countries and the Middle East and most of the data are from Western countries. Sociocultural determinants haven't been getting the same attention as biological and psychological factors when studying sexual health.

Objectives: To assess the prevalence of FSD in the Arab and Middle Eastern world and understand the sociocultural determinants related.

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Alexithymia, a predictor in chronic illnesses, like cardiovascular and bipolar disorder (CD-BD), could be improved with a virtual reality (VR) cognitive remediation program. This secondary analysis of a previous randomized controlled trial (RCT) evaluates alexithymia improvement and its factors in an experimental group versus a control group, exploring extensions to individuals with comorbid non-psychiatric chronic conditions. A feasibility cross-over RCT (ClinicalTrials.

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Article Synopsis
  • Adiponectin and leptin are key hormones that impact the brain's function, particularly during the critical postpartum period for mothers and their infants, affecting maternal mood and infant development.
  • * The study aims to investigate how levels of adiponectin and leptin in mothers’ blood and breast milk relate to infant neurodevelopment at 6 and 12 months old and maternal mental health during the first year postpartum.
  • * A prospective cohort study is underway, having recruited 68 out of 95 mother-infant pairs as of September 2023, focusing on various factors like maternal depression, infant growth, and nutritional habits to improve healthcare strategies for mothers and infants.*
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The Brazilian Academy of Sciences commissioned a report on mental health to develop strategies for addressing mental health challenges in the post-pandemic world. These strategies should be evidence-based, culturally sensitive, resource-efficient, and promote equity, while being tailored to specific contexts. The report's proposals are meant for discussion among S20 participating Academies of Sciences, serving as a collection of ideas to influence global mental health policies, rather than mandatory guidelines.

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Background: Receptive vaginal penetration skills have been implicated in the etiology, explanatory models, and treatment of genito-pelvic pain penetration disorder (GPPPD). However, there are no psychometric skills measures designed to screen, assess, and stratify GPPPD.

Aim: We aimed to develop and psychometrically evaluate a new scale-the Vaginal Penetration Skills Scale (VPSS)-to screen, assess, and stratify GPPPD.

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