Wholegrain oat diet changes the expression of genes associated with intestinal bile acid transport.

Scope: The molecular mechanisms underlying the cholesterol-lowering properties of oats are only partly known. To study possible pathways involved, we investigated gene expressions in the liver and small intestine of mice fed oats.

Method And Results: Cholesterol and bile acids were analyzed in plasma and feces from LDL-receptor deficient (LDLr ) mice fed Western diet with wholegrain oats.