Resveratrol protects Lactobacillus reuteri against HO- induced oxidative stress and stimulates antioxidant defenses through upregulation of the dhaT gene.

Understanding of the mechanisms implicated in the protective role of probiotic bacteria is of the utmost scientific interest. This study provides original insight into the genetic and molecular basis of the responses of Lactobacillus reuteri PL503 against hydrogen peroxide (HO)-induced oxidative stress. Six experimental groups were considered depending on the addition and concentration of HO and resveratrol: 1.