Clinical profile and outcomes of pediatric scrub typhus associated with elevated hepatic transaminases.

Background: Hepatic transaminase (HT) elevation is frequently seen in children with scrub typhus (ST), but the clinical implication of this common finding is not known.

Objective: To describe the clinical profile and outcome of pediatric ST with elevated hepatic transaminase.

Methods: In this prospective cohort study, all children < 12 years of age presenting with fever for ≥ 5 days and positive immunoglobulin M (IgM) serology for ST were included.

Prospective Study to Assess the Response to Therapy and Its Predictors in Children with Scrub Typhus.

Doxycycline is the drug of choice for pediatric scrub typhus (ST) while azithromycin is considered as an equally effective alternative. This study was undertaken to assess the response to therapy and its predictors in pediatric ST cases treated with doxycycline and azithromycin. Children ≤12 year with fever ≥7 days were screened for ST by IgM ELISA (positive if optical density >0.

Clinical profile and predictors of severity in paediatric scrub typhus with pulmonary involvement.

Pulmonary involvement is common in children with scrub typhus. Our paper outlines the clinical characteristics of pulmonary involvement and analyses the predictors of its severity. All scrub typhus serology-positive (optical density >0.

Drug therapy in Pediatric Scrub Typhus - Is 'not Giving Azithromycin' a Risk Factor for PICU Admission?

NA.

Predictors of Severity in Pediatric Scrub Typhus.

Objective: To identify the factors that can predict the severity of scrub typhus in children.

Methods: This prospective study was conducted at a tertiary care teaching hospital between November 2014 to October 2016. All children <12y of age admitted with fever for more than 7d and positive IgM ELISA for scrub typhus were included in the study.

Clinical Profile of Scrub Typhus Meningoencephalitis among South Indian Children.

Re-emerging scrub typhus is gaining recognition as an important cause of paediatric meningoencephalitis in tropics. We studied the clinical profile of scrub typhus meningoencephalitis (STME) in children <12 years. Of 270 serology-confirmed cases of scrub typhus, 14 (5%) had features consistent with STME and 9 (64%) of these children were between 5 and 12 years of age; 12 (85%) children presented to the hospital during the second week of illness.

Clinico - Laboratory Profile of Scrub Typhus - An Emerging Rickettsiosis in India.

Objective: To study the clinical and laboratory profile of pediatric scrub typhus in rural south India.

Methods: This is a descriptive study of the clinical and laboratory features of 117 children with IgM ELISA proven scrub typhus out of 448 children, who were admitted in the Pediatric ward of a tertiary care hospital, during the study period of November 2014 through March 2015.

Results: Fever was present in all 117 children, with mean duration of fever at admission as 9 d.