Clinical profile, risk factors, and clinical outcomes in patients of venous thromboembolism at a tertiary care center.

Background: Venous thromboembolism (VTE) commonly presents as either deep-vein thrombosis (DVT) or pulmonary embolism (PE). Despite rapid advances in its diagnostic and therapeutic modalities, it still leads to significant morbidity and mortality.

Objectives: Our study predominantly aims at studying the clinical profile, risk factors, and the clinical outcomes in VTE patients presenting to a single tertiary care center to rapidly detect the disease and use appropriate thrombo-prophylaxis.

More future synergies and less trade-offs between forest ecosystem services with natural climate solutions instead of bioeconomy solutions.

To reach the Paris Agreement, societies need to increase the global terrestrial carbon sink. There are many climate change mitigation solutions (CCMS) for forests, including increasing bioenergy, bioeconomy, and protection. Bioenergy and bioeconomy solutions use climate-smart, intensive management to generate high quantities of bioenergy and bioproducts.

Impact of Levodopa in Lung Functions in Patients with Parkinson Disease.

Background: Parkinson's disease (PD) is the second-most common neurodegenerative disorder known primarily by its motor symptomatology. These motor manifestations are also hypothesised to affect the respiratory muscular function of PD patients contributing to restrictive pattern of ventilatory dysfunction. Previous reports attempting to detect these abnormalities through spirometric assessments have been inconclusive.

An improved ion chromatographic method for fast and sensitive determination of N-methylpyrrolidine in cefepime hydrochloride.

An alternative ion chromatographic method to the existing USP method for the determination of N-methylpyrrolidine (NMP) in cefepime hydrochloride is developed. The cefepime in solution behaves as a strong cation and gets retained in the analytical column, leading to reduction in column capacity and irreproducible retention time. The retained drug has to be removed with a special rinsing solution, followed by re-equilibration with the mobile phase.

Ion chromatographic determination of residual phase transfer catalyst in active pharmaceutical ingredient.

A new ion chromatography method with non-suppressed conductivity detection has been developed for the quantification of residual phase transfer catalyst-tetrabutylammonium bromide (TBAB) in an active pharmaceutical drug, Levetiracetam. Separation conditions are optimized to get a clear separation of TBAB from drug impurities using a Metrosep Cation C2-150 column. Conditions are also optimized to separate tetramethylammonium bromide, tetraethylammonium bromide, and tetrapropylammonium bromide, which are also used as phase transfer catalysts in several syntheses.

Matrix elimination ion chromatography method for trace level azide determination in irbesartan drug.

Ultra-trace analysis of azide in complicated Irbesartan sample matrix is achieved by the in-line sample preparation technique. Sodium azide is the precursor of Irbesartan, which is used as an anti-hypertensive drug. Due to the toxic nature of sodium azide, reliable determination of azide in Irbesartan is necessary.