Ticagrelor is used to inhibit acute coronary syndrome, but its poor solubility and low bioavailability limit its in-vivo efficacy. The purpose of this study was to manufacture an optimized ticagrelor-loaded self-microemulsifying drug-delivery system in the form of tablets to enhance the solubility and dissolution of that drug. A preliminary study was conducted to determine the extent of turbidity of oils for this study, and a pseudoternaryphase diagram was used to identify the region of formation of microemulsion with 3 ratios (1:1,1:2, and 1:3).
View Article and Find Full Text PDFACS Omega
February 2019
[This corrects the article DOI: 10.1021/acsomega.8b03221.
View Article and Find Full Text PDFHerein, a magnetically separable reduced graphene oxide (rGO)-supported CoFeO-TiO photocatalyst was developed by a simple ultrasound-assisted wet impregnation method for efficient photocatalytic H production. Integration of CoFeO with TiO induced the formation of Ti sites that remarkably reduced the optical band gap of TiO to 2.80 eV from 3.
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