An Approach for Cognitive Evaluation and Management of Grade 5 Arteriovenous Malformation-Associated Thalamic Dementia: A Case Report and Literature Review.

The clinical approach to managing high-grade arteriovenous malformations (AVMs) has been challenging due to its various presentations, surgical risk of complications, and impact on patients' quality of life. We report a case of a 57-year-old female who experienced recurrent seizures and progressive cognitive decline secondary to a grade 5 cerebellar AVM. We reviewed the patient's presentation and clinical course.

Clinical Spectrum of Monogenic Infantile-Onset Inflammatory Bowel Disease.

Very-early-onset IBD and infantile-onset IBD is extremely rare in children. There is paucity of data with regards to clinical profile and outcome of children with infantile-onset IBD from India. The clinicolaboratory profile, molecular genetic testing and treatment details of 8 children diagnosed with monogenic infantile-onset IBD during 2015-2020 is described here.

Liquid Mosquito Repellent Ingestion in Children.

Objectives: Hydrocarbons are a common cause of accidental poisoning in children, with kerosene being the most implicated agent in rural parts of India. However, lately, liquid mosquito repellent ingestion is emerging as an important cause of hydrocarbon (kerosene) poisoning in urban households.

Methods: This is a retrospective case series over a 5-y period (January 2013 - December 2017) of children with accidental liquid mosquito repellent ingestion presenting to the pediatric emergency.

Production of chitin deacetylase by Aspergillus flavus in submerged conditions.

Chitosan is a biopolymer obtained by deacetylation of chitin and has been proven to have various applications in industry and biomedicine. Deacetylation of chitin using the enzyme chitin deacetylase (CDA) is favorable in comparison to the hazardous chemical method involving strong alkali and high temperature. A fungal strain producing CDA was isolated from environmental samples collected from coastal regions of South Kerala, India.

Purification and characterisation of an acidic and antifungal chitinase produced by a Streptomyces sp.

An extremely acidic extracellular chitinase produced by a Streptomyces sp. was purified 12.44-fold by ammonium sulphate precipitation, ion-exchange chromatography and gel-permeation chromatography and further characterised.

Production, purification and properties of fungal chitinases--a review.

After cellulose, chitin is the second most abundant organic and renewable polysaccharide in nature. This polymer is degraded by enzymes called chitinases which are a part of the glycoside hydrolase family. Chitinases have many important biophysiological functions and immense potential applications especially in control of phytopathogens, production of chito- oligosaccharides with numerous uses and in treatment and degradation of chitinous biowaste.

Growth failure in children with chronic myeloid leukemia receiving imatinib is due to disruption of GH/IGF-1 axis.

Background: The frontline treatment for chronic myeloid leukemia (CML) is tyrosine kinase inhibitor therapy. There is increasing evidence that imatinib results in growth failure in children; etiology is unclear.

Procedure: The cross-sectional study was conducted from January 2011 to June 2012 in a pediatric oncology unit.

Broadband all-optical modulation in hydrogenated-amorphous silicon waveguides.

We demonstrate broadband all-optical modulation in low loss hydrogenated-amorphous silicon (a-Si:H) waveguides. Significant modulation (approximately 3 dB) occurs with a device of only 15 microm without the need for cavity interference effects in stark contrast to an identical crystalline silicon waveguide. We attribute the enhanced modulation to the significantly larger free-carrier absorption effect of a-Si:H, estimated here to be alpha = 1.

Optical nonlinearities in hydrogenated-amorphous silicon waveguides.

We experimentally measure the optical nonlinearities in hydrogenated-amorphous silicon (a-Si:H) waveguides through the transmission of ultra-short pulses. The measured two-photon absorption coefficient beta is 4.1 cm/GW and we obtain a 3.

Generation of amplitude-shift-keying optical signals using silicon microring resonators.

We demonstrate the generation of amplitude-shift-keying (ASK) optical signals using a system of parallel microring resonators. By independently modulating two symmetric microring resonators arranged in a Mach-Zehnder configuration, we realize the generation of three levels. The proposed scheme can be extended to any number of logic levels, which effectively increases the data rate of an optical link using slower modulators.